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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 258 - 262 (5page)
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초록· 키워드
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The KMT2A (formerly MLL) gene is associated with at least 10% of all cases of acute leukemia. More than 80 translocation partner genes of KMT2A have been discovered to date, six of which have been identified on the long arm of chromosome 17. Among these, the MLLT6 (formerly AF17) gene is located at 17q12 and fuses with the KMT2A gene in rare cases of acute leukemia. We report here a case of AML with a KMT2A/MLLT6 fusion that was confirmed using molecular genetic methods. According to a literature review, this is the first reported case of AML with a KMT2A/MLLT6 fusion in Korea.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Huret JL / 2006 / MLL(myeloid/lymphoid or mixed lineage leukemia) / Atlas Genet Cytogenet Oncol Haematol 10:83~87
Burillo-Sanz S / 2018 / MLL-rearranged acute myeloid leukemia : Influence of the genetic partner in allo-HSCT response and prognostic factor of MLL 3’ region mRNA expression / Eur J Haematol 100:436~443
Deqing Hu / 2016 / Epigenetics of hematopoiesis and hematological malignancies / Genes Dev 30:2021~2041
Bennett JM / 1985 / Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group / Ann Intern Med 103:620~625
Schoch C / 2003 / AML with 11q23/MLL abnormalities as defined by the WHO classification : incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases / Blood 102:2395~2402
Burillo-Sanz S / 2018 / MLL-rearranged acute myeloid leukemia : Influence of the genetic partner in allo-HSCT response and prognostic factor of MLL 3’ region mRNA expression / Eur J Haematol 100:436~443
Deqing Hu / 2016 / Epigenetics of hematopoiesis and hematological malignancies / Genes Dev 30:2021~2041
Bennett JM / 1985 / Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group / Ann Intern Med 103:620~625
Schoch C / 2003 / AML with 11q23/MLL abnormalities as defined by the WHO classification : incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases / Blood 102:2395~2402
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