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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 315 - 327 (13page)
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초록· 키워드
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Solanum nigrum is a medicinal plant belonging to the Solanaceae family. It possesses various therapeutic properties such as anticancer, antioxidant, hepatoprotective, antiulcer, antiinflammatory, antihyperlipidemic, antidiabetic, antibacterial, and antiseizure properties. Numerous secondary metabolites have been isolated from S. nigrum, including (+) syringaresinol (II), (+)-medioresinol (III), scopoletin (IV), tetracosanoic acid (V), and beta-sitosterol (IV). They also contain a variety of toxic secondary metabolites such as alpha-Solanine and alpha-Chaconine, which are steroidal glycoalkaloids. Here, we showed the potential of CRISPR/Cas9 technology to improve and enhance the plant architecture, secondary metabolites, and therapeutic applications in eliminating toxic compounds, especially solanine and chaconine, in S. nigrum.
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참고문헌 (61)
참고문헌 신청
Aboul-Enein AM / 2014 / Potent anticancer and antioxidant activities of active ingredients separated from solanum nigrum and cassia Italica extracts / J Arid L Stud 21:145~152
Almazini MA-I / 2009 / Antibacterial activity of the solasodine of solanum nigrum against bacterial isolates from the wounds / Basrah J Vet Res 8:137~147
Midori A Arai / 2014 / Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1–DNA-complex formation / Beilstein Journal of Organic Chemistry 10:134~140
Liliana Bejarano / 2000 / Glycoalkaloids in potato tubers: the effect of variety and drought stress on the ?-solanine and ?-chaconine contents of potatoes / Journal of the Science of Food and Agriculture 80(14):2096~2100
Boulos L / 1983 / Medicinal plants of North Africa / Reference Publications Inc
Almazini MA-I / 2009 / Antibacterial activity of the solasodine of solanum nigrum against bacterial isolates from the wounds / Basrah J Vet Res 8:137~147
Midori A Arai / 2014 / Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1–DNA-complex formation / Beilstein Journal of Organic Chemistry 10:134~140
Liliana Bejarano / 2000 / Glycoalkaloids in potato tubers: the effect of variety and drought stress on the ?-solanine and ?-chaconine contents of potatoes / Journal of the Science of Food and Agriculture 80(14):2096~2100
Boulos L / 1983 / Medicinal plants of North Africa / Reference Publications Inc
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