지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제17권 제3호
- 발행연도
- 2019.1
- 수록면
- 446 - 449 (4page)
이용수
초록· 키워드
오류제보하기
Methylphenidate (MPH) is the most preferred drug for treatment of the attention deficit hyperactivity disorder (ADHD). Here, we aimed to discuss the possible effects and mechanisms of MPH on precocious puberty (PP) via a case series with seven children who had normal body mass index. In this case series we evaluated seven children with ADHD, who had received MPH for at least 6 months (0.5 mg/kg/dose three times a day, maximum 60 mg) and admitted to Department of Pediatric Endocrinology with PP symptoms. The mean age was 8.16 years. Basal hormonal levels (luteinizing hormone [LH], follicle stimulating hormone, and estrogen/testosterone) were within normal range. Results of LH-releasing hormone stimulation tests demonstrated central pubertal responses. Glutamine, dopamine and noradrenaline are most important excitatory neurotransmitters that have a role at the beginning of puberty. The effect of MPH, cumulating dopamine and noradrenaline in the synaptic gap could be associated with the acceleration of puberty with the excitatory effect of dopamine’s gonadotropin-releasing hormone (GnRH) release, excitatory effect of noradrenaline’s GnRH release and the disappearance of GnRH receptor expression suppressor effect on prolactin disinhibitory effect.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Polanczyk G / 2007 / The worldwide prevalence of ADHD : a systematic review and metaregression analysis / Am J Psychiatry 164:942~948
Barkley RA / 2002 / The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder / J Abnorm Psychol 111:279~289
Gumy C / 2010 / Prevalence of methylphenidate prescription among school-aged children in a Swiss population : increase in the number of prescriptions in the Swiss Canton of Vaud, from 2002 to 2005, and changes in patient demographics / J Atten Disord 14:267~272
Kuczenski R / 1997 / Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine : comparison with amphetamine / J Neurochem 68:2032~2037
Montagnini BG / 2014 / Effects of repeated administration of methylphenidate on reproductive parameters in male rats / Physiol Behav 133:122~129
Barkley RA / 2002 / The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder / J Abnorm Psychol 111:279~289
Gumy C / 2010 / Prevalence of methylphenidate prescription among school-aged children in a Swiss population : increase in the number of prescriptions in the Swiss Canton of Vaud, from 2002 to 2005, and changes in patient demographics / J Atten Disord 14:267~272
Kuczenski R / 1997 / Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine : comparison with amphetamine / J Neurochem 68:2032~2037
Montagnini BG / 2014 / Effects of repeated administration of methylphenidate on reproductive parameters in male rats / Physiol Behav 133:122~129
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Gonadotropin-releasing hormone stimulation test and diagnostic cutoff in precocious puberty: a mini review
Annals of Pediatirc Endocrinology & Metabolism
2020 .01
-
성조숙증 여아들의 임상적 특징 및 진단별 성선자극호르몬 분비호르몬 GnRH (Gonado Tropin Releasing Hormone) 검사결과의 비교분석평가
핵의학기술
2016 .01
-
Commentary on "Effect of gonadotropin-releasing hormone agonist treatment on near final height in girls with central precocious puberty and early puberty"
Annals of Pediatirc Endocrinology & Metabolism
2023 .03
-
Preliminary Investigation of Association between Methylphenidate and Serum Growth Markers in Children with Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Case-Control Study
소아청소년정신의학
2020 .07
-
특발성 성조숙증으로 진단받은 환아 2례에 대한 증례보고
대한한방소아과학회지
2017 .01
-
Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty
Annals of Pediatirc Endocrinology & Metabolism
2021 .12
-
Does Methylphenidate Affect Cystometric Parameters in Spontaneously Hypertensive Rats?
International Neurourology Journal
2015 .01
-
Diurnal variation of gonadotropin levels in girls with early stages of puberty
Annals of Pediatirc Endocrinology & Metabolism
2017 .01
-
통계자료를 통한 국내 성조숙증 진료현황 분석
대한한방소아과학회지
2016 .01
-
성조숙증 치료에 대한 임상 연구 동향 -최근 중의학 저널을 중심으로-
대한한방소아과학회지
2017 .01
-
성조숙증과 수면에 관한 임상연구동향
대한한방소아과학회지
2021 .11
-
Methylphenidate Induced Lip and Tongue Biting
Clinical Psychopharmacology and Neuroscience
2018 .01
-
The utilization of basal luteinizing hormone in combination with the basal luteinizing hormone and follicle-stimulating hormone ratio as a diagnostic tool for central precocious puberty in girls
Annals of Pediatirc Endocrinology & Metabolism
2023 .06
-
Commentary on "Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty"
Annals of Pediatirc Endocrinology & Metabolism
2021 .12
-
Body image and depression in girls with idiopathic precocious puberty treated with gonadotropin-releasing hormone analogue
Annals of Pediatirc Endocrinology & Metabolism
2016 .01
-
Basal serum luteinizing hormone value as the screening biomarker in female central precocious puberty
Annals of Pediatirc Endocrinology & Metabolism
2019 .01
-
호르몬 치료를 받은 초등학교 여아의 성조숙증 경험
한국간호교육학회지
2019 .11
-
Association between Attention Deficit Hyperactivity Disorder Medication and Depression: A 10-year Follow-up Self-controlled Case Study
Clinical Psychopharmacology and Neuroscience
2022 .05
-
국민건강보험 데이터베이스를 이용한 한국의 소아와 성인에서 주의력결핍 과잉행동장애의 진단율 및 약물 사용 추세 연구
신경정신의학
2021 .11
-
Systematic Review of Suicidal Behaviors Related to Methylphenidate and Atomoxetine in Patients With Attention Deficit Hyperactivity Disorder
소아청소년정신의학
2023 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0