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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 163 - 177 (15page)
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초록· 키워드
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The ability to accurately evaluate skeletal muscle microvascular blood flow has broad clinical applications for understanding the regulation of skeletal muscle perfusion in health and disease states. Contrast-enhanced ultrasound (CEU) perfusion imaging, a technique originally developed to evaluate myocardial perfusion, is one of many techniques that have been applied to evaluate skeletal muscle perfusion. Among the advantages of CEU perfusion imaging of skeletal muscle is that it is rapid, safe and performed with equipment already present in most vascular medicine laboratories. The aim of this review is to discuss the use of CEU perfusion imaging in skeletal muscle. This article provides details of the protocols for CEU imaging in skeletal muscle, including two predominant methods for bolus and continuous infusion destruction-replenishment techniques. The importance of stress perfusion imaging will be highlighted, including a discussion of the methods used to produce hyperemic skeletal muscle blood flow. A broad overview of the disease states that have been studied in humans using CEU perfusion imaging of skeletal muscle will be presented including: (1) peripheral arterial disease; (2) sickle cell disease; (3) diabetes; and (4) heart failure. Finally, future applications of CEU imaging in skeletal muscle including therapeutic CEU imaging will be discussed along with technological developments needed to advance the field.
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등록된 정보가 없습니다.
참고문헌 (57)
참고문헌 신청
Joyner MJ / 2015 / Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs / Physiol Rev 95:549~601
Calbet JA / 2012 / Skeletal muscle vasodilatation during maximal exercise in health and disease / J Physiol 590:6285~6296
Gliemann L / 2018 / Methods for the determination of skeletal muscle blood flow : development, strengths and limitations / Eur J Appl Physiol 118:1081~1094
Dunford EC / 2018 / Cardiovascular aging and the microcirculation of skeletal muscle : using contrast-enhanced ultrasound / Am J Physiol Heart Circ Physiol 315:H1194~1199
Lindner JR / 2002 / Microvascular rheology of Definity microbubbles after intra-arterial and intravenous administration / J Am Soc Echocardiogr 15:396~403
Calbet JA / 2012 / Skeletal muscle vasodilatation during maximal exercise in health and disease / J Physiol 590:6285~6296
Gliemann L / 2018 / Methods for the determination of skeletal muscle blood flow : development, strengths and limitations / Eur J Appl Physiol 118:1081~1094
Dunford EC / 2018 / Cardiovascular aging and the microcirculation of skeletal muscle : using contrast-enhanced ultrasound / Am J Physiol Heart Circ Physiol 315:H1194~1199
Lindner JR / 2002 / Microvascular rheology of Definity microbubbles after intra-arterial and intravenous administration / J Am Soc Echocardiogr 15:396~403
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