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In this research, a multi-slit prompt-gamma camera was developed to locate the distal dose falloff of theproton beam spots in spot scanning proton therapy. To see the performance of the developed camera,therapeutic proton beams were delivered to a solid plate phantom and then the prompt gammas fromthe phantom were measured using the camera. Our results show that the camera locates the 90% distaldose falloff (¼ d90%), within about 2e3 mm of error for the spots which are composed 3.8 108 protonsor more. The measured location of d90% is not very sensitive to the irradiation depth of the proton beam(i.e., the depth of proton beam from the phantom surface toward which the camera is located). Considering the number of protons per spot for the most distal spots in typical treatment cases (i.e., 2 Gydose divided in 2 fields), the camera can locate d90% only for a fraction of the spots depending on thetreatment cases. However, the information of those spots is still valuable in that, in the multi-slit promptgammacamera, the distal dose falloff of the spots is located solely based on prompt gamma measurement,i.e., not referring to Monte Carlo simulation

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