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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.6
- 수록면
- 2,213 - 2,220 (8page)
- DOI
- https://doi.org/10.1016/j.net.2021.12.027
이용수
이 논문의 연구 히스토리 (3)
2022
Performance prediction of gamma electron vertex imaging (GEVI) system for interfractional range shift detection in spot scanning proton therapy
김성훈
,
정종휘
,
구영모
외 2명
Nuclear Engineering and Technology
2022.06
학술저널
Upgrade of gamma electron vertex imaging system for high-performance range verifi cation in pencil beam scanning proton therapy
김성훈
,
정종휘
,
구영모
외 4명
Nuclear Engineering and Technology
2022.03
학술저널
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초록· 키워드
오류제보하기
The maximum dose delivery at the end of the beam range provides the main advantage of using protontherapy. The range of the proton beam, however, is subject to uncertainties, which limit the clinicalbenefits of proton therapy and, therefore, accurate in vivo verification of the beam range is desirable. Forthe beam range verification in spot scanning proton therapy, a prompt gamma detection system, calledas gamma electron vertex imaging (GEVI) system, is under development and, in the present study, theperformance of the GEVI system in spot scanning proton therapy was predicted with Geant4 Monte Carlosimulations in terms of shift detection sensitivity, accuracy and precision. The simulation results indicated that the GEVI system can detect the interfractional range shifts down to 1 mm shift for the casesconsidered in the present study. The results also showed that both the evaluated accuracy and precisionwere less than 1e2 mm, except for the scenarios where we consider all spots in the energy layer for alocal shifting. It was very encouraging results that the accuracy and precision satisfied the smallest distalsafety margin of the investigated beam energy (i.e., 4.88 mm for 134.9 MeV).
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