지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 159 - 167 (9page)
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초록· 키워드
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Background and Purpose An interarm blood pressure difference (IABD) is independently related to the occurrence of cardiovascular disease and mortality. Cerebral small-vessel diseases (SVDs) are important risk factors for stroke, cognitive dysfunction, and mortality. We aimed to determine whether IABD is related to cerebral SVDs. Methods This study included 1,205 consecutive noncardioembolic ischemic stroke patients as confirmed by brain MRI and simultaneously measured the bilateral brachial blood pressures. We investigated cerebral SVDs based on high-grade white-matter hyperintensities (HWHs), presence of cerebral microbleeds (CMBs), high-grade perivascular spaces (HPVSs), and asymptomatic lacunar infarctions (ALIs) on brain MRI. Results In multivariate logistic regression, an interarm systolic blood pressure difference (IASBD) ≥10 mm Hg was independently related to the existence of HWHs [odds ratio (OR)= 1.94, 95% CI=1.32–2.84, p=0.011] and had a tendency to be associated with the presence of HPVSs (OR=1.45, 95% CI=0.49–2.23, p=0.089) and ALIs (OR=1.42, 95% CI=0.96–2.11, p= 0.052), but not with the presence of CMBs (OR=1.09, 95% CI=0.73–1.61, p=0.634). In multivariate linear regression adjusted for age, sex, and variables with p<0.1 in the univariate analysis, IASBD ≥10 mm Hg and interarm diastolic blood pressure difference ≥10 mm Hg were significantly correlated with an increased total burden of SVDs (β=0.080 and p=0.006, and β=0.065 and p=0.023, respectively). Conclusions This study found that IABD ≥10 mm Hg was associated with the presence and increased burden of cerebral SVDs in noncardioembolic stroke patients. This suggests that IABD ≥10 mm Hg could be a useful indicator of the presence and burden of cerebral SVDs in stroke patients.
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참고문헌 (29)
참고문헌 신청
Clark CE / 2016 / Prevalence of systolic inter-arm differences in blood pressure for different primary care populations : systematic review and meta-analysis / Br J Gen Pract 66:e838~e847
Kim J / 2013 / Interarm blood pressure difference and mortality in patients with acute ischemic stroke / Neurology 80:1457~1464
Clark CE / 2012 / Association of a difference in systolic blood pressure between arms with vascular disease and mortality : a systematic review and meta-analysis / Lancet 379:905~914
Aboyans V / 2007 / The vital prognosis of subclavian stenosis / J Am Coll Cardiol 49:1540~1545
Fei Han / 2018 / Prevalence and Risk Factors of Cerebral Small Vessel Disease in a Chinese Population-Based Sample / 대한뇌졸중학회지 20(2):239~246
Kim J / 2013 / Interarm blood pressure difference and mortality in patients with acute ischemic stroke / Neurology 80:1457~1464
Clark CE / 2012 / Association of a difference in systolic blood pressure between arms with vascular disease and mortality : a systematic review and meta-analysis / Lancet 379:905~914
Aboyans V / 2007 / The vital prognosis of subclavian stenosis / J Am Coll Cardiol 49:1540~1545
Fei Han / 2018 / Prevalence and Risk Factors of Cerebral Small Vessel Disease in a Chinese Population-Based Sample / 대한뇌졸중학회지 20(2):239~246
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