지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.12
- 수록면
- 511 - 518 (8page)
- DOI
- 10.17495/easdl.2019.12.29.6.511
이용수
초록· 키워드
오류제보하기
Obesity is a cause of various metabolic diseases, so prevention and treatment are important. Recently, there has been an increasing interest in natural foods that promote fat breakdown or inhibit fat accumulation. The objective of this study was to investigate the amelioratory effect of acorn and acorn mook ethanol extract on reactive oxygen species (ROS) production and lipid accumulation in differentiated 3T3-L1 cells. First, antioxidant activity and the expression of C/EBP-β, C/EBP-α, PPAR-γ, and aP2 level by western blotting in 3T3-L1 cells of acorn ethanol extract were examined. Total polyphenol and total flavonoid contents of acorn ethanol extract were 476.44±14.70 mg TAE/g and 102.91±13.14 mg QE/g, respectively. AEtOH suppressed C/EBP-β, C/EBP-α, PPAR-γ expression, an adipogenesis related transcription factor, and inhibited aP2 expression in 3T3L-1 cells. Based on the first results, we made acorn mook and treated 3T3-L1 cells with acorn mook ethanol extract to investigate its inhibitory effect on ROS production and lipid accumulation. Acorn mook ethanol extract significantly inhibited ROS production and lipid accumulation in 3T3-L1 cells. These results suggest that acorn mook might be an effective potential agent to ameliorate obesity.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (26)
참고문헌 신청
Auddy B / 2003 / Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases / J Ethnopharmacol 84(2-3):131~138
Bradford MM / 1976 / A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / Anal Biochem 72(1-2):248~254
Chukir T / 2018 / Pharmacotherapy for obesity in individuals with type 2diabetes / Expert Opin Pharmacother 19(3):223~231
El-Jack AK / 1999 / Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPα / J Biol Chem 274(12):7946~7951
GutiFinger T / 1974 / Quantitative changes in some unsaponifiable components of soya bean oil due to refining / J Sci Food Agric 25(9):1143~1147
Bradford MM / 1976 / A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding / Anal Biochem 72(1-2):248~254
Chukir T / 2018 / Pharmacotherapy for obesity in individuals with type 2diabetes / Expert Opin Pharmacother 19(3):223~231
El-Jack AK / 1999 / Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPα / J Biol Chem 274(12):7946~7951
GutiFinger T / 1974 / Quantitative changes in some unsaponifiable components of soya bean oil due to refining / J Sci Food Agric 25(9):1143~1147
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
겔화제 첨가에 따른 쌀 묵의 품질특성
한국식품조리과학회지
2017 .01
-
고장초 추출 용매의 에탄올 함량에 따른 항산화, 항염증, 항알러지, 미백 활성 비교 분석
생명과학회지
2017 .09
-
국내산 해조류 4종의 물과 에탄올 추출물이 3T3-L1에서 지방세포 분화에 미치는 영향
동아시아식생활학회지
2015 .12
-
생쥐 뇌세포에 알코올이 미치는 영향
대한임상검사과학회지
2015 .01
-
Silibinin Inhibits Adipogenesis and Induces Apoptosis in 3T3-L1 Adipocytes
한국미생물·생명공학회지
2017 .01
-
Antioxidant Activity, Macamide B Content and Muscle Cell Protection of Maca (Lepidium meyenii) Extracted Using Ultrasonification-Assisted Extraction
한국미생물·생명공학회지
2020 .01
-
Chungkookjang Ethanol Extracts reduces IL6 Expression
한국미생물학회 학술대회논문집
2015 .04
-
비파 부위별 추출물이 3T3-L1 세포와 돼지 지방전구세포의 분화에 미치는 효과
한국지역사회생활과학회지
2016 .11
-
Erratum: Induction of apoptotic cell death in human bladder cancer cells by ethanol extract of Zanthoxylum schinifolium leaf, through ROS-dependent inactivation of the PI3K/ Akt signaling pathway
Nutrition Research and Practice
2025 .04
-
Erratum: Induction of apoptotic cell death in human bladder cancer cells by ethanol extract of Zanthoxylum schinifolium leaf, through ROS-dependent inactivation of the PI3K/ Akt signaling pathway
Nutrition Research and Practice
2025 .04
-
Anti-Melanogenesis and Anti-Wrinkle Effects of Sargassum micracanthum Extracts
한국미생물·생명공학회지
2016 .01
-
Ethanol Production from Glycerol Using Immobilized Pachysolen tannophilus During Microaerated Repeated-Batch Fermentor Culture
Journal of Microbiology and Biotechnology
2015 .01
-
Antioxidant Effects of Water and Ethanol Extracts prepared with Kiwi Pomace
동아시아식생활학회 학술발표대회논문집
2024 .11
-
Inhibitory effect of ethanolic extract of Abeliophyllum distichum leaf on 3T3-L1 adipocyte differentiation
Nutrition Research and Practice
2021 .10
-
Inhibitory effect of ethanolic extract of Abeliophyllum distichum leaf on 3T3-L1 adipocyte differentiation
Nutrition Research and Practice
2021 .10
-
갯완두(Lathyrus japonicus) 에탄올 추출물의 항산화 및 항염증 효능
한국해양바이오학회지
2023 .06
-
Paeonia lactiflora Inhibits Cell Wall Synthesis and Triggers Membrane Depolarization in Candida albicans
Journal of Microbiology and Biotechnology
2017 .01
-
Cell Death Inhibition Effect of Antioxidant Activity by 630 and 850 nm LEDs in RAW264.7 Cells
Current Optics and Photonics
2024 .10
-
Conditions for Preparing Glycyrrhiza uralensis Extract for Inhibiting Biofilm Formation of Streptococcus mutans
목재공학(Journal of the Korean Wood Science and Technology)
2019 .01
-
증류수와 에탄올로 추출한 어성초 염액의 색소 특성 및 염색성
한국생활과학회지
2020 .12
이 논문의 저자 정보
이 논문과 함께 이용한 논문
무선 전력 전송용 고효율 공진기 설계
장요한
,
권재순
,
박재수
외 1명
한국전자파학회논문지
2011
.09
감귤피 효소적 추출물의 지방세포에서의 항비만 효과
장예빈
,
강희주
,
김주상
외 1명
한국식품과학회지
2021
.04
꾸지뽕 신초 엽위별 잎 추출물의 항비만 효과
박주하
,
궈루
,
강혜미
외 6명
생명과학회지
2021
.02
바나나(Musa acuminate Colla) 껍질 추출물의 항비만 활성
김령현
,
이승철
,
김교남
한국식품영양과학회지
2020
.12
뽕잎 추출물 기원 Flavonoid Rich Fraction의 항비만효과
고은지
,
류병렬
,
양수진
외 4명
한국약용작물학회지
2020
.12
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2020-594-000228354