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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 705 - 712 (8page)
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Eosinophilic granulomatosis with polyangiitis (EGPA) is one form of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Identical to what has been called Churg-Strauss syndrome, EGPA exhibits both allergic and vasculitis features. EGPA was firstdescribed as a syndrome consisting of asthma, fever, eosinophilia, and organ involvement including heart failure, neuropathy, andkidney damage, by Churg and Strauss in 1951. On the basis of the 2012 Chapel Hill Consensus Conferences Nomenclature of Vasculitis,EGPA comprises three typical allergic components, including asthma, peripheral eosinophilia, and eosinophil-rich granulomaof the respiratory tracts. EGPA has three clinical and histological stages. The first is an allergic stage composed of asthma and sinusitis,and the second is an eosinophilic stage characterised by peripheral hypereosinophilia and intra-organ infiltration of eosinophils. The last is a vasculitic stage, including necrotising inflammation of small vessels and end-organ damage. In this review, we describethe classification criteria for EGPA and recommendations for the evaluation and management of EGPA with conventional andnewly suggested drugs for EGPA. Also, we discuss a variety of clinical aspects such as predictive values for prognosis and associationswith other Th2-mediated diseases and hepatitis B virus.
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참고문헌 (52)
참고문헌 신청
Jennette JC / 2013 / 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides / Arthritis Rheum 65:1~11
Lionaki S / 2012 / Classification of antineutrophil cytoplasmic autoantibody vasculitides : the role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis / Arthritis Rheum 64:3452~3462
Churg J / 1951 / Allergic granulomatosis, allergic angiitis, and periarteritis nodosa / Am J Pathol 27:277~301
Vaglio A / 2009 / Churg-Strauss syndrome / Kidney Int 76:1006~1011
Jennette JC / 1994 / Nomenclature of systemic vasculitides. Proposal of an international consensus conference / Arthritis Rheum 37:187~192
Lionaki S / 2012 / Classification of antineutrophil cytoplasmic autoantibody vasculitides : the role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis / Arthritis Rheum 64:3452~3462
Churg J / 1951 / Allergic granulomatosis, allergic angiitis, and periarteritis nodosa / Am J Pathol 27:277~301
Vaglio A / 2009 / Churg-Strauss syndrome / Kidney Int 76:1006~1011
Jennette JC / 1994 / Nomenclature of systemic vasculitides. Proposal of an international consensus conference / Arthritis Rheum 37:187~192
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