Evolution of Visual Pigments and Related Molecules

Hisatomi, Osamu; Yamamoto, Shintaro; Kobayashi, Yuko; Honkawa, Hanayo; Takahashi, Yusuke; Tokunaga, Fumio

추천

검색

자료유형: 학술저널

저자정보: Hisatomi, Osamu (Department of Earth and Space Science, Graduate School of Science, Osaka University) Yamamoto, Shintaro (Department of Earth and Space Science, Graduate School of Science, Osaka University) Kobayashi, Yuko (Department of Earth and Space Science, Graduate School of Science, Osaka University) Honkawa, Hanayo (Department of Earth and Space Science, Graduate School of Science, Osaka University) Takahashi, Yusuke (Department of Earth and Space Science, Graduate School of Science, Osaka University) Tokunaga, Fumio (Department of Earth and Space Science, Graduate School of Science, Osaka University)

저널정보: 한국광과학회 Journal of photoscience : an international journal officail organ of the korean society of photoscience Journal of photoscience : an international journal officail organ of the korean society of photoscience 제9권 제2호

발행연도: 2002.1

수록면: 41 - 43 (3page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

In photoreceptor cells, light activates visual pigments consisting of a chromophore (retinal) and a protein moiety (opsin). Activated visual pigments trigger an enzymatic cascade, called phototransduction cascade, in which more than ten phototransduction proteins are participating. Two types of vertebrate photoreceptor cells, rods and cones, play roles in twilight and daylight vision, respectively. Cones are further classified into several subtypes based on their morphology and spectral sensitivity. Though the diversities of vertebrate photoreceptor cells are crucial for color discrimination and detection of light over a wider range of intensities, the molecular mechanism to characterize the photoreceptor types remains unclear. We investigated the amino acid sequences of about 50 vertebrate opsins, and found that these sequences can be classified into five fundamental subfamilies. Clear relationships were found between these subfamilies and their characteristic spectral sensitivities. In addition to opsins, we studied other phototransduction proteins. The amino acid sequences of phototransduction proteins can be classified into a few subfamilies. Even though their spectral sensitivity is considerably different, cones fundamentally share the phototransduction protein isoforms which are different from those found in rods. It is suggested that the difference in phototransduction proteins between rods and cones is responsible for their sensitivity to light. Isoforms and their selective expression may characterize individual photoreceptor cells, thus providing us with physiological functions such as color vision and daylight/twilight visions.

#Phototransduction #Molecular evolution #Visual system #Opsin #Photoreceptor cells

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!