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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 82 - 87 (6page)
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Objectives : Recently the case of lactobacillus mixture culture fluid appliment was reported. In this study, anti-inflamation effects and anti-allergy effects were studied by stimulus of lactobacillus mixture culture fluid extracts in HaCaT cells. Methods : The atopic dermatitis were induced by TNF-${\alpha}$ and interferon-${\gamma}$ in HaCaT cells. TARC/CCL17, MDC/CCL22, RANTES/CCL5 and ROS production were investigated to explain anti-inflamation and allergy effects of lactobacillus mixture culture fluid with cell-enzyme-linked Immunosorbent assay in 450 nm, 485 nm, 535 nm with spectro-fluorometer. Results : The extracts of lactobacillus mixture culture fluid were decreased TARC/CCL17, MDC/CCL22, RANTES/CCL5 expressions and ROS production with a concentration dependent manner. Conclusions : The effects mechanism of Lactobacillus mixed culture fluid for atopic dermatitis symptoms were considered to be explain anti-inflamation and allergy effects via control of cytokine, chemokine and ROS production, and the fluid could be applied in skin cells directly. But classified AD symptom degrees reported in clinical case before as Reaction Period, Reduction Period, Effect Period, Reproduction Period and Rebound Period could not be explained. Further study will be expected.
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참고문헌 (22)
참고문헌 신청
Howlett S. / 1999 / Emotional dysfunction, child-family relationships and childhood atopic dermatitis / Br J Dermatol 140:381~384
Foolad N / 2012 / Armstrong AW(2012) Effect of nutrient supplementation on atopic dermatitis in children / Arch Dermatol 17:1~6
Hwang EK. / 2012 / The Clinical Significance of Fungal Allergy in Patients with Atopic Dermatitis. Ajou:Department of Medical Sciences
David TJ / 1984 / Low serum zinc in children with atopic eczema / Br J Dermatol 111:597~601
Searing DA / 2010 / Vitamin D in atopic dermatitis, asthma and allergic diseases / Immunol Allergy Clin North Am 30:397~409
Foolad N / 2012 / Armstrong AW(2012) Effect of nutrient supplementation on atopic dermatitis in children / Arch Dermatol 17:1~6
Hwang EK. / 2012 / The Clinical Significance of Fungal Allergy in Patients with Atopic Dermatitis. Ajou:Department of Medical Sciences
David TJ / 1984 / Low serum zinc in children with atopic eczema / Br J Dermatol 111:597~601
Searing DA / 2010 / Vitamin D in atopic dermatitis, asthma and allergic diseases / Immunol Allergy Clin North Am 30:397~409
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