지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Objective : Postoperative pain is one of the major complaints of patients after lumbar fusion surgery. The authors evaluated the effects of intravenous patient controlled analgesia (IV-PCA) using fentanyl or sufentanil on postoperative pain management and pain-related complications. Methods : Forty-two patients that had undergone surgery with lumbar instrumentation and fusion at single or double levels constituted the study cohort. Patients were equally and randomly allocated to a sufentanil group (group S) or a fentanyl group (group F) for patient controlled analgesia (PCA). Group S received sufentanil at a dose of $4{\mu}g/kg$ IV-PCA and group F received fentanyl $24{\mu}g/kg$ IV-PCA. A numeric rating scale (NRS) of postoperative pain was applied before surgery, and immediately and at 1, 6, and 24 hours (hrs) after surgery. Oswestry disability index (ODI) scores were obtained before surgery and one month after surgery. Opioid-related side effects were also evaluated. Results : No significant intergroup difference was observed in NRS or ODI scores at any of the above-mentioned time points. Side effects were more frequent in group F. More specifically, nausea, vomiting rates were significantly higher (p=0.04), but pruritus, hypotension, and headache rates were non-significantly different in the two groups. Conclusion : Sufentanil displayed no analgesic advantage over fentanyl postoperatively. However, sufentanil should be considerable for patients at high risk of GI issues, because it had lower postoperative nausea and vomiting rates than fentanyl.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Bianconi M / 2004 / The pharmacokinetics and efficacy of ropivacaine continuous wound instillation after spine fusion surgery / Anesth Analg 98:166~172
Bost P / 1999 / Postoperative pain assessment in head and neck cancer surgery: benefit of patient controlled analgesia (PCA) / Ann Otolaryngol Chir Cervicofac 116:154~161
Brownstein MJ / 1993 / A brief history of opiates, opioid peptides, and opioid receptors / Proc Natl Acad Sci USA 90:5391~5393
Cata JP / 2008 / Patientcontrolled epidural analgesia (PCEA) for postoperative pain control after lumbar spine surgery / J Neurosurg Anesthesiol 20:256~260
Cohen BE / 1997 / Postoperative pain control after lumbar spine fusion. Patient-controlled analgesia versus continuous epidural analgesia / Spine 22:1892~1896
Bost P / 1999 / Postoperative pain assessment in head and neck cancer surgery: benefit of patient controlled analgesia (PCA) / Ann Otolaryngol Chir Cervicofac 116:154~161
Brownstein MJ / 1993 / A brief history of opiates, opioid peptides, and opioid receptors / Proc Natl Acad Sci USA 90:5391~5393
Cata JP / 2008 / Patientcontrolled epidural analgesia (PCEA) for postoperative pain control after lumbar spine surgery / J Neurosurg Anesthesiol 20:256~260
Cohen BE / 1997 / Postoperative pain control after lumbar spine fusion. Patient-controlled analgesia versus continuous epidural analgesia / Spine 22:1892~1896
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