A Patient with Neutropenia and Splenomegaly: A Case Report from Department of Family Medicine in Tertiary Hospital Center

Cho Jaehee; Song Youhyun; Lee Jiyeon; Lee Daeun; Go Yunsun; Kang Hee Cheol

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자료유형: 학술저널

저자정보: Cho Jaehee (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea) Song Youhyun (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea) Lee Jiyeon (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea) Lee Daeun (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea) Go Yunsun (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea) Kang Hee Cheol (Department of Family Medicine Severance Hospital Yonsei University College of Medicine Seoul Korea)

저널정보: 대한가정의학회 Korean Journal of Family Medicine Korean Journal of Family Medicine 제42권 제3호

발행연도: 2021.1

수록면: 250 - 254 (5page)

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Pancytopenia represents a unique challenge for primary care doctors and its etiological causes encompass various specialties, including hematology and rheumatology. Despite the existence of effective tests such as bone marrow biopsy and immunoassays to rule out the potential causes of pancytopenia, it is often difficult to pinpoint the exact diagnosis. In this case report, we have described such a ‘gray zone’ patient, who presented with pancytopenia, neutropenia, and splenomegaly, and was being treated for fungal pneumonia before being transferred to Severance Hospital (department of family medicine). As the patient had a 10-year history of multiple, long-term hospital admissions that were having a severely debilitating impact on the quality of life, we performed a partial splenic embolization as a potential cure for the symptoms. Although this induced acute blood count recovery, it failed to prevent eventual mortality from septic shock.

#Pancytopenia #Neutropenia #Hypersplenism #Embolization #Therapeutic

참고문헌 (8)

참고문헌 신청

Weinzierl EP / 2013 / The differential diagnosis and bone marrow evaluation of new-onset pancytopenia / Am J Clin Pathol 139:9~29

Bae MH / 2015 / Pancytopenia or Bicytopenia in a Korean Tertiary Care Center; Etiological profile based on bone marrow examination and suggestion for diagnostic approach / Blood 126:5610

Valent P / 2012 / Idiopathic cytopenia of undetermined significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), and their distinction from low risk MDS / Leuk Res 36:1~5

Kavanaugh AF / 2002 / Guidelines for immunologic laboratory testing in the rheumatic diseases : anti-DNA antibody tests / Arthritis Rheum 47:546~555

Attar SM / 2010 / Medical conditions associated with a positive anti-double-stranded deoxyribonucleic acid / Saudi Med J 31:781~787

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