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자료유형
학술저널
저자정보
Donald Hathaway III (Division of Research & Academic Affairs Larkin Health System) Pandav Krunal (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Patel Madhusudan (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Riva-Moscoso Adrian (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Singh Bishnu Mohan (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Patel Aayushi (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Min Zar Chi (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Singh-Makkar Sarabjot (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Sana Muhammad Khawar (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Sanchez-Dopazo Rafael (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Desir Rockeven (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Fahem Michael Maher Mourad (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Manella Susan (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Rodriguez Ivan (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Alvarez Alina (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.) Abreu Rafael (Division of Research & Academic Affairs Larkin Health System South Miami FL USA.)
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제52권 제4호
발행연도
2020.1
수록면
478 - 495 (18page)

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The rapid international spread of severe acute respiratory syndrome coronavirus 2 responsible for coronavirus disease 2019 (COVID-19) has posed a global health emergency in 2020. It has affected over 52 million people and led to over 1.29 million deaths worldwide, as of November 13th, 2020. Patients diagnosed with COVID-19 present with symptoms ranging from none to severe and include fever, shortness of breath, dry cough, anosmia, and gastrointestinal abnormalities. Severe complications are largely due to overdrive of the host immune system leading to “cytokine storm”. This results in disseminated intravascular coagulation, acute respiratory distress syndrome, multiple organ dysfunction syndrome, and death. Due to its highly infectious nature and concerning mortality rate, every effort has been focused on prevention and creating new medications or repurposing old treatment options to ameliorate the suffering of COVID-19 patients including the immune dysregulation. Omega-3 fatty acids are known to be incorporated throughout the body into the bi-phospholipid layer of the cell membrane leading to the production of less pro-inflammatory mediators compared to other fatty acids that are more prevalent in the Western diet. In this article, the benefits of omega-3 fatty acids, especially eicosapentaenoic acid and docosahexaenoic acid, including their anti-inflammatory, immunomodulating, and possible antiviral effects have been discussed.

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