지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 397 - 402 (6page)
이용수
초록· 키워드
오류제보하기
Metastasis is one of the most important factors in the prognosis and choice of treatment strategyof patients with head and neck squamous cell carcinoma (HNSCC). In order for disseminationto take effect, tumor cells must segregate themselves from their primary tumor site andmigrate into the blood or lymphatic vessels. To detach from the primary tumor, cells have todisrupt cell-cell adhesion, remodel of the cytoskeleton, change in cell-matrix adhesion and finallyreturn to their original condition. This temporary and reversible process is known as theepithelial-mesenchymal transition (EMT). EMT is a dynamic cellular process in which epithelialcells acquire mesenchymal features and suggested to play an important role during cancerinvasion and metastasis. With the recent explosion of knowledge on EMT in carcinogenesis,EMT has become an interesting target for anticancer therapy. This review article first highlightsat the biochemical changes that take place around the cell membrane called cadherinswitching during EMT and looks at the current literature on EMT in HNSCC. Understandingthe mechanism of EMT will provide insight to the metastasis of HNSCC and may lead to thedevelopment of novel anti-cancer therapeutics.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
Chaturvedi AK / 2013 / Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers / J Clin Oncol 31(36):4550~4559
Hashim D / 2019 / Head and neck cancer prevention: From primary prevention to impact of clinicians on reducing burden / Ann Oncol 30(5):744~756
Attar E / 2010 / Head and neck cancer in a developing country: A population based perspective across 8 years / Oral Oncol 46(8):591~596
Puri SK / 2003 / Significance of extracapsular lymph node metastases in patients with head and neck squamous cell carcinoma / Curr Opin Otolaryngol Head Neck Surg 11(2):119~123
Martinez-Useros J / 2015 / The challenge of blocking a wider family members of EGFR against head and neck squamous cell carcinomas / Oral Oncol 51(5):423~430
Hashim D / 2019 / Head and neck cancer prevention: From primary prevention to impact of clinicians on reducing burden / Ann Oncol 30(5):744~756
Attar E / 2010 / Head and neck cancer in a developing country: A population based perspective across 8 years / Oral Oncol 46(8):591~596
Puri SK / 2003 / Significance of extracapsular lymph node metastases in patients with head and neck squamous cell carcinoma / Curr Opin Otolaryngol Head Neck Surg 11(2):119~123
Martinez-Useros J / 2015 / The challenge of blocking a wider family members of EGFR against head and neck squamous cell carcinomas / Oral Oncol 51(5):423~430
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
119구급대원의 현장 및 이송 중 응급처치 경험에 대한 현상학적 연구
한국응급구조학회지
2022 .12
-
포커스그룹인터뷰(FGI)를 통한 응급구조사의 보수교육에 대한 인식
한국응급구조학회지
2024 .08
-
Early Growth Response Protein-1 Involves in Transforming Growth factor-β1 Induced Epithelial-Mesenchymal Transition and Inhibits Migration of Non-Small-Cell Lung Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
1급 응급구조사의 자격에 대한 입법론적 고찰
한국응급구조학회지
2019 .01
-
응급구조사 국가시험 응시 자격기준에 관한 고찰
한국응급구조학회지
2021 .08
-
Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells
Toxicological Research
2015 .06
-
군 응급구조사의 업무분석 및 직무만족도
한국응급구조학회지
2015 .01
-
Prognostic significance of programmed cell death-ligand 1 expression on immune cells and epithelialmesenchymal transition expression in patients with hepatocellular carcinoma
Annals of Surgical Treatment and Research
2023 .11
-
황금탕의 족돌기세포에서의 EMT 억제 효능
동의생리병리학회지
2020 .04
-
Epithelial-Mesenchymal Transition in Chronic Rhinosinusitis
Journal of Rhinology
2024 .07
-
Immunohistochemical Expression of Epithelial-Mesenchymal Transition Markers in Early Gastric Cancer: Cancer Tissue versus Noncancer Tissue
Clinical Endoscopy
2019 .01
-
국내 응급구조사 이미지에 대한 연구동향 고찰
한국응급구조학회지
2023 .04
-
119구급대의 스마트의료지도 직무수행능력 영향요인
한국응급구조학회지
2019 .01
-
119 구급대원의 화학사고 대응역량 및 교육요구도
한국응급구조학회지
2024 .04
-
Tumor-Associated Macrophages Derived TGF-β-Induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells through Smad2,3-4/Snail Signaling Pathway
Cancer Research and Treatment
2019 .01
-
119 구급대원의 직무스트레스, 소진이 삶의 질에 미치는 영향†
한국응급구조학회지
2018 .01
-
119 구급대원의 건강상태 및 건강관리 프로그램 운영 실태
한국응급구조학회지
2017 .01
-
Quantitative Changes in Tumor-Associated M2 Macrophages Characterize Cholangiocarcinoma and their Association with Metastasis
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
악성 흑색종에서 CGM이 유도하는 세포자멸사와 상피간엽이행 억제 효과
한국구강보건과학회지
2024 .06
-
Short Low Concentration Cisplatin Treatment Leads to an Epithelial Mesenchymal Transition-like Response in DU145 Prostate Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0