지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 86 - 90 (5page)
이용수
초록· 키워드
오류제보하기
Precise allergy diagnosis and effective allergen specific immunotherapy are largely dependent on the quality of allergen extract. Anew extract of Dermatophagoides farinae was commercially developed by Prolagen. The allergenic properties of the new extractwere compared with those of other commercial products. The allergenic properties of the new extract were compared accordingto protein concentration, protein profiles, major allergen (Der f 1) contents, and allergenic potency to those for three commerciallyavailable extracts imported in Korea (Jubilant HollisterStier Allergy, Lofarma S.p.A., and Stallergenes Greer). Protein concentrationsvaried up to 2.62-fold (0.404 to 1.057 mg/mL), and Der f 1 contents varied up to 11.3-fold (3.597 to 40.688 μg/mL). Protein profiles of the extracts showed no major discrepancies, although there were some differences in SDS-PAGE band intensities,reflecting protein concentrations. Allergen potency ranged from 37038 to 60491 PAU/mL. The Prolagen product was highestin terms of protein concentration and allergen potency. The Lofarma product displayed Der f 1 content similar to that in Prolagen(19.4 μg/mg vs. 19.3 μg/mg). Endotoxin levels varied 8.9-fold (1020 to 8985 EU/mL). The newly developed house dust mite extractshowed equal or better allergenic properties than available commercial extracts. This new product may be useful for better diagnosticsand allergen-specific immunotherapeutics.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
정경용 / 2011 / Optimization of Allergen Standardization / Yonsei Medical Journal 52(3):393~400
Slater JE / 2012 / The US Food and Drug Administration review of the safety and effectiveness of nonstandardized allergen extracts / J Allergy Clin Immunol 129:1014~1019
Klimek L / 2015 / Diagnostic test allergens used for in vivo diagnosis of allergic diseases are at risk : a European Perspective / Allergy 70:1329~1331
정경용 / 2014 / Current Status of Standardization of Inhalant Allergen Extracts in Korea / Allergy, Asthma & Immunology Research 6(3):196~200
정경용 / 2012 / Standardization of House Dust Mite Extracts in Korea / Allergy, Asthma & Immunology Research 4(6):346~350
Slater JE / 2012 / The US Food and Drug Administration review of the safety and effectiveness of nonstandardized allergen extracts / J Allergy Clin Immunol 129:1014~1019
Klimek L / 2015 / Diagnostic test allergens used for in vivo diagnosis of allergic diseases are at risk : a European Perspective / Allergy 70:1329~1331
정경용 / 2014 / Current Status of Standardization of Inhalant Allergen Extracts in Korea / Allergy, Asthma & Immunology Research 6(3):196~200
정경용 / 2012 / Standardization of House Dust Mite Extracts in Korea / Allergy, Asthma & Immunology Research 4(6):346~350
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
알레르겐의 물리생화학적 특성
Allergy Asthma & Respiratory Diseases
2016 .01
-
알레르기 진단을 위한 원인 항원 패널 선정 최적화 연구
대한이비인후-두경부외과학회지
2019 .01
-
알레르겐 표준화
Allergy Asthma & Respiratory Diseases
2018 .01
-
In Vitro Evaluation of Allergen Potencies of Commercial House Dust Mite Sublingual Immunotherapy Reagents
Allergy, Asthma & Immunology Research
2015 .01
-
Mold Allergens in Respiratory Allergy: From Structure to Therapy
Allergy, Asthma & Immunology Research
2015 .01
-
Allergen Sensitization Pattern by Sex: A Cluster Analysis in Korea
Annals of Dermatology
2017 .01
-
Efficacy of Allergen Immunotherapy for Allergic Asthma in Real World Practice
Allergy, Asthma & Immunology Research
2020 .01
-
Profiles of IgE Sensitization to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20 in Korean House Dust Mite Allergy Patients
Allergy, Asthma & Immunology Research
2015 .01
-
Avoidance Behavior against Positive Allergens Detected with a Multiple Allergen Simultaneous Test Immunoblot Assay in Patients with Urticaria: Factors Associated with Avoidance Success/Failure
Annals of Dermatology
2016 .01
-
Performance of the PROTIATM Allergy-Q® System in the Detection of Allergen-specific IgE: A Comparison With the ImmunoCAP® System
Allergy, Asthma & Immunology Research
2015 .01
-
Spectrum of Allergen Sensitization to Food and Inhalant Allergens Across All Ages
Allergy, Asthma & Immunology Research
2020 .01
-
Comparison of Component-Resolved Diagnosis by Using Allergen Microarray With the Conventional Tests in Allergic Rhinitis Patients: The First Using in Korea
Clinical and Experimental Otorhinolaryngology
2015 .01
-
Pollen/Fruit Syndrome: Clinical Relevance of the Cypress Pollen Allergenic Gibberellin-Regulated Protein
Allergy, Asthma & Immunology Research
2019 .01
-
Validation of PROTIA™ Allergy-Q 64 Atopy® as a Specific IgE Measurement Assay for 10 Major Allergen Components
Allergy, Asthma & Immunology Research
2019 .01
-
Allergen-Specific Immunotherapies for Food Allergy
Allergy, Asthma & Immunology Research
2018 .01
-
Allergen Sensitization and Its Association With Allergic Diseases in the Korean Population: Results From the 2019 Korea National Health and Nutrition Examination Survey
Allergy, Asthma & Immunology Research
2024 .09
-
Expression in Escherichia coli and Purification of Folded rDer p 20, the Arginine Kinase From Dermatophagoides pteronyssinus: A Possible Biomarker for Allergic Asthma
Allergy, Asthma & Immunology Research
2021 .01
-
생활화학제품의 알레르기반응가능 향료성분 함유 현황 및 동시 출현 패턴 조사
한국환경보건학회지
2022 .08
-
The Role of Lipids in Development of Allergic Responses
Immune Network
2017 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0