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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 556 - 556 (1page)
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Colorectal carcinoma (CRC) is one of the most common and aggressive malignant carcinomas. In this study, we aimed to investigate the anticancer effects and the underlying mechanism of action of harmine hydrochloride (HMH), a hydrophilic and stable substance that is easily absorbed by tissues and similar to harmine, in human CRC HCT116 cells. HMH inhibited the growth, colony formation, and migration abilities of HCT116 cells. Additionally, HMH induced G2 cell cycle arrest by reducing the expression of p-cdc2, cdc2, and cyclin B1, in a dose-dependent manner, as well as the expression of ^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10669227');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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