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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 260 - 271 (12page)
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초록· 키워드
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It is well known that patients with type 2 diabetes mellitus (T2DM) are at an increased risk of morbidity and mortality from atherosclerotic cardiovascular (CV) complications. Previously, the concept that diabetes mellitus (DM) is a “coronary artery disease (CAD)risk equivalent” was widely accepted, implying that all DM patients should receive intensive management. However, considerableevidence exist for wide heterogeneity in the risk of CV events among T2DM patients and the concept of a “CAD risk equivalent”has changed. Recent guidelines recommend further CV risk stratification in T2DM patients, with treatment tailored to the risk level. Although imaging modalities for atherosclerotic cardiovascular disease (ASCVD) have been used to improve risk prediction, thereis currently no evidence that imaging-oriented therapy improves clinical outcomes. Therefore, controversy remains whether weshould screen for CVD in asymptomatic T2DM. The coexistence of T2DM and heart failure (HF) is common. Based on recent CVoutcome trials, sodium glucose cotransporter-2 inhibitors and glucagon like peptide-1 receptor agonists are recommended who haveestablished ASCVD, indicators of high risk, or HF because of their demonstrated benefits for CVD. These circumstances have led toan increasing emphasis on ASCVD and HF in T2DM patients. In this review, we examine the literature published within the last 5years on the risk assessment of CVD in asymptomatic T2DM patients. In particular, we review recent guidelines regarding screeningfor CVD and research focusing on the role of coronary artery calcium, coronary computed tomography angiography, and carotid intima-media thickness in asymptomatic T2DM patients.
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참고문헌 (57)
참고문헌 신청
Fowler MJ / 2008 / Microvascular and macrovascular complications of diabetes / Clin Diabetes 26:77~82
Grundy SM / 1999 / Diabetes and cardiovascular disease : a statement for healthcare professionals from the American Heart Association / Circulation 100:1134~1146
Gu K / 1998 / Mortality in adults with and without diabetes in a national cohort of the U. S. population, 1971-1993 / Diabetes Care 21:1138~1145
Bessueille L / 2015 / Inflammation : a culprit for vascular calcification in atherosclerosis and diabetes / Cell Mol Life Sci 72:2475~2489
Shi Y / 2017 / Macro-and microvascular endothelial dysfunction in diabetes / J Diabetes 9:434~449
Grundy SM / 1999 / Diabetes and cardiovascular disease : a statement for healthcare professionals from the American Heart Association / Circulation 100:1134~1146
Gu K / 1998 / Mortality in adults with and without diabetes in a national cohort of the U. S. population, 1971-1993 / Diabetes Care 21:1138~1145
Bessueille L / 2015 / Inflammation : a culprit for vascular calcification in atherosclerosis and diabetes / Cell Mol Life Sci 72:2475~2489
Shi Y / 2017 / Macro-and microvascular endothelial dysfunction in diabetes / J Diabetes 9:434~449
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