후각장애 환자에서의 향의 종류, 선호도에 따른 후각훈련의효과 차이

박도양; 김동영; 하정호; 이주호; 김현준

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자료유형: 학술저널

저자정보: 박도양 (아주대학교) 김동영 (서울대학교) 하정호 (아주대학교 의과대학 이비인후과학교실) 이주호 (아주대학교 의과대학 이비인후과학교실) 김현준 (아주대학교)

저널정보: 대한비과학회 Journal of Rhinology Journal of Rhinology Vol.26 No.2

발행연도: 2019.1

수록면: 92 - 98 (7page)

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Background and Objectives: Recently, the prevalence of olfactory dysfunction has increased with pollution and populationadequate. Treatment by olfactory training has been suggested as an alternative method, but there is no protocol for olfactorytraining with odorants familiar to Koreans. Also, no studies have analyzed the effects of individual preference in terms of personalizedmedicine. This study compared the effectiveness of olfactory training according to patient odor preference. Materials and Method: The prospective study was performed in patients with olfactory dysfunction and used 8 total odorants. After a survey of preference for the odorants, patients were divided into two groups, one group performed olfactory trainingwith 3 preferred odorants, whereas the other group performed training with odorants they did not prefer. Also, the effects ofolfactory training in the two groups were compared by KVSS threshold, discrimination, identification score, and subjective VASscore of olfaction. Olfactory testing was performed before and after training for 4 and 12 weeks. Results: There was no demographic difference between the two groups. After olfactory training, the preference group showedstatistically significant improvement in threshold, identification, TDI score, and VAS score. Conversely, there was no significantchange of olfactory function in the non-preference group. Conclusion: Thus, we conclude that odorants of olfactory training should be applied depending on cultural preferences, andthat the preferred odorants of each individual patient will have a greater therapeutic effect on olfactory dysfunction compared tonon-preferred odorants.

#Olfaction dysfunction #Treatment #Olfactory training #Preference.

참고문헌 (19)

참고문헌 신청

Hummel T / 2009 / Effects of olfactory training in patients with olfactory loss / The Laryngoscope 119:496~499

Lee WH / 2013 / Prevalence of subjective olfactory dysfunction and its risk factors: korean national health and nutrition examination survey / PloS one 8:e62725

Upadhyay UD / 2004 / Olfactory loss as a result of toxic exposure / Otolaryngologic Clinics of North America 37:1185~1207

이지은 / 2017 / 후각과 알츠하이머병 / Journal of Rhinology 24(1):1~7

Doty RL / 2012 / Olfactory dysfunction in Parkinson disease / Nature reviews Neurology 8:329~339

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