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논문 기본 정보

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학술저널
저자정보
Kim Jeong-Whun (Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University College of Medici) Kim Hyo sang (Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University College of Medici) Kim Minju (Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University College of Medici) Kim Su Hwan (Department of Biomedical Engineering Seoul National University College of Medicine Seoul Korea.) Cho Sung-Woo (Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University College of Medici) Kim Jin Youp (Department of Otorhinolaryngology-Head and Neck Surgery Seoul National University College of Medici)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.6
발행연도
2021.1
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1 - 10 (10page)

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Background: The patients with coronavirus disease 2019 (COVID-19), a worldwide pandemic infection, frequently complain of olfactory disorders. However, psychophysical olfactory tests performed by an examiner are very difficult in these highly infectious patients. This study aimed to develop and validate a questionnaire for olfactory function that can be readily used to evaluate olfactory loss. Methods: Fourteen smell-related questions were created based on smells familiar to Koreans. Among them, questions with a κ value of 0.6 or higher were finally selected through a test-retest reliability analysis. The correlations between the scores of the olfactory questionnaire and those of olfactory function tests (Butanol Threshold Test [BTT] and Cross Cultural Smell Identification Test [CCSIT]) were analyzed. To evaluate the predictive ability of the questionnaire and elicit cutoff values, receiver operating characteristic (ROC) curves were generated. Results: Out of the 14 questions in the questionnaire, 11 (κ > 0.6) were selected for the olfactory questionnaire. We analyzed 2,273 subjects, and there was a significant correlation between the total score of the olfactory questionnaire and the BTT (r = 0.643, P < 0.001) or CCSIT (r = 0.615, P < 0.001) scores. ROC curves for the olfactory questionnaire, BTT, and CCSIT all demonstrated high predictive power to discriminate anosmia and severe hyposmia from normosmia. Regarding mild to moderate hyposmia, however, ROC curve for the olfactory questionnaire alone showed high predictive power of discrimination from normosmia. Based on the results of ROC curves among the subclasses, we suggest the classification of the total score of the questionnaire as 0–4, 5–17, 18–27, 28–41, and 42–44, for anosmia, severe hyposmia, moderate hyposmia, mild hyposmia, and normosmia, respectively. Conclusion: The total scores of the questionnaires correlated with the BTT and CCSIT scores. The symptom questionnaire for olfactory dysfunction may be useful as an alternative tool for olfactory function testing, when unavailable.
#Smell #Olfaction Disorders #Surveys and Questionnaires #Sensation #Anosmia

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참고문헌 (28)

참고문헌 신청
홍성문 / 2011 / Relationship between the Korean Version of the Sniffin’ Stick Test and the T&T Olfactometer in the Korean Population / Clinical and Experimental Otorhinolaryngology 4(4):184~187 dbpia 김재명 / 2014 / Olfactory Identification Test Using Familiar Distracters for Koreans / Clinical and Experimental Otorhinolaryngology 7(1):19~23 dbpia 박철원 / 2009 / Development of Guideline for Rating the Physical Impairment of Otolaryngologic Field / Journal of Korean Medical Science 24:258~266 dbpia Doty RL / 1984 / University of Pennsylvania Smell Identification Test : a rapid quantitative olfactory function test for the clinic / Laryngoscope 94(2 Pt 1):176~178 google schola Hummel T / 1997 / ‘Sniffin' sticks’ : olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold / Chem Senses 22(1):39~52 google schola

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