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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
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Background: We investigated the association between pentraxin 3 (PTX3), a novel inflammatory marker, and bone mineral density (BMD) in the general Korean population. Methods: We selected a sub-cohort of 1,440 subjects (757 men and 683 women) from participants in the community-based Dong-gu Study. The mean age was 66.0 ± 8.1 years for men and 63.7 ± 7.9 years for women. The plasma PTX3 levels were measured using an enzyme-linked immunosorbent assay, and BMD was measured in the femoral neck and lumbar spine using dual-energy X-ray absorptiometry. Linear regression analyses were used to evaluate the association between the plasma PTX3 levels and BMD. Results: PTX3 was inversely associated with the BMD of the lumbar spine (P = 0.010) and femoral neck (P < 0.001) in men but not in women. For men, the association with the BMD of the femoral neck remained after adjustment for multiple comparison (P = 0.020). Conclusion: This study suggests that PTX3 levels might be inversely associated with BMD in elderly men.
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참고문헌 (29)
참고문헌 신청
Looker AC / 1998 / Updated data on proximal femur bone mineral levels of US adults / Osteoporos Int 8(5):468~489
Iki M / 2001 / Bone mineral density of the spine, hip and distal forearm in representative samples of the Japanese female population: Japanese Population-Based Osteoporosis (JPOS) Study / Osteoporos Int 12(7):529~537
Cheng XG / 2007 / Age-related bone mineral density, bone loss rate, prevalence of osteoporosis, and reference database of women at multiple centers in China / J Clin Densitom 10(3):276~284
박은정 / 2014 / Prevalence of Osteoporosis in the Korean Population Based on Korea National Health and Nutrition Examination Survey (KNHANES), 2008--2011 / Yonsei Medical Journal 55(4):1049~1057
Ock M / 2015 / Estimating quality-adjusted life-year loss due to noncommunicable diseases in Korean adults through to the year 2040 / Value Health 18(1):61~66
Iki M / 2001 / Bone mineral density of the spine, hip and distal forearm in representative samples of the Japanese female population: Japanese Population-Based Osteoporosis (JPOS) Study / Osteoporos Int 12(7):529~537
Cheng XG / 2007 / Age-related bone mineral density, bone loss rate, prevalence of osteoporosis, and reference database of women at multiple centers in China / J Clin Densitom 10(3):276~284
박은정 / 2014 / Prevalence of Osteoporosis in the Korean Population Based on Korea National Health and Nutrition Examination Survey (KNHANES), 2008--2011 / Yonsei Medical Journal 55(4):1049~1057
Ock M / 2015 / Estimating quality-adjusted life-year loss due to noncommunicable diseases in Korean adults through to the year 2040 / Value Health 18(1):61~66
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