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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 354 - 360 (7page)
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It is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretionin past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence ofobesity, the main cause of diabetes has increased. Thus, there is still a question as to whether the main pathophysiology of currentKorean T2DM is insulin resistance or an insulin secretion defect. Because various anti-diabetes medications having differentmechanisms of action are currently used as therapeutics, it is important to understand which of these factors is the main physiologyin the development of diabetes in Koreans. In this review, we review changes in obesity prevalence, insulin resistance and insulinsecretion defects in Korean T2DM during three decades.
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참고문헌 (37)
참고문헌 신청
Defronzo RA / 2009 / Banting lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2diabetes mellitus / Diabetes 58:773~795
Warram JH / 1990 / Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents / Ann Intern Med 113:909~915
Park SW / 1999 / Pathogenetic heterogeneity of type 2 diabetes mellitus in Korea / J Korean Diabetes Assoc 23:62~69
Yoon KH / 2000 / Pathogenesis of type 2 diabetes in Korea / J Korean Diabetes Assoc 24:397~403
Min HK / 1992 / Clinical characteristics of diabetes in Korea / J Korean Diabetes Assoc 16:163~174
Warram JH / 1990 / Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents / Ann Intern Med 113:909~915
Park SW / 1999 / Pathogenetic heterogeneity of type 2 diabetes mellitus in Korea / J Korean Diabetes Assoc 23:62~69
Yoon KH / 2000 / Pathogenesis of type 2 diabetes in Korea / J Korean Diabetes Assoc 24:397~403
Min HK / 1992 / Clinical characteristics of diabetes in Korea / J Korean Diabetes Assoc 16:163~174
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