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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한뇌혈관외과학회 Journal of Cerebrovascular and Endovascular Neurosurgery Journal of Cerebrovascular and Endovascular Neurosurgery Vol.20 No.2
- 발행연도
- 2018.1
- 수록면
- 112 - 119 (8page)
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초록· 키워드
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Objective : Cerebral microbleeds (CMBs) are known as the neuroimaging markers of risk in stroke and dementia. Many studies on CMBs in elderly patients with hemorrhagic or ischemic stroke have been reported; however, reports on CMBs in young populations with intracerebral hemorrhage (ICH) are lacking. Materials and Methods : A total of 272 patients aged 18-54 years presented to our hospital with ICH between December 2009 and August 2017. Among these, CMB presence, count, and topography with respect to ICH were evaluated on magnetic resonance imaging (MRI) gradient echo images (GREs). We also evaluated the prevalence and risk factors of CMBs. Results : Among 272 patients, only 66 underwent GRE T2-weighted MRI. CMBs were detected in 40 patients (61%), with 29 (73%) being of the multifocal type. Among the 219 CMBs, 150 (68.5%) were of the deep type and 69 (31.5%) of the lobar type. CMB prevalence was higher in men. In multivariate logistic regression analysis, history of hypertension (adjusted odds ratio [aOR], 4.048; 95% confidence interval [CI], 1.14-14.32; p = 0.030), and male sex (aOR, 4.233; 95% CI, 1.09-16.48; p = 0.037) were independently associated with CMBs. Conclusion : In young patients who presented with spontaneous ICH, CMBs were highly prevalent in 61% of patients and strongly associated with history of hypertension and male sex.
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참고문헌 (38)
참고문헌 신청
Al-Shahi Salman R / 2008 / Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board / Stroke 39(12):3222~3230
Charidimou A / 2016 / White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy / Neurology 86(6):505~511
Charidimou A / 2013 / Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy / Neurology 81(7):626~632
Charidimou A / 2014 / White matter perivascular spaces: an MRI marker in pathology-proven cerebral amyloid angiopathy? / Neurology 82(1):57~62
Charidimou A / 2013 / Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings / Neuroradiology 55(6):655~674
Charidimou A / 2016 / White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy / Neurology 86(6):505~511
Charidimou A / 2013 / Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy / Neurology 81(7):626~632
Charidimou A / 2014 / White matter perivascular spaces: an MRI marker in pathology-proven cerebral amyloid angiopathy? / Neurology 82(1):57~62
Charidimou A / 2013 / Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings / Neuroradiology 55(6):655~674
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