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자료유형
학술저널
저자정보
양다해 (고신대학교 의과대학 진단검사의학과) 이운형 (고신대학교)
저널정보
고신대학교 의과대학 고신대학교 의과대학 학술지 고신대학교 의과대학 학술지 제33권 제1호
발행연도
2018.1
수록면
29 - 40 (12page)

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Objectives: Blood culture is a one of the most important procedure for diagnosis and treatment of infectious disease, but distribution of pathogenic species and the antimicrobial susceptibility can be vary from pathogen, individual trait, regional or environmental features. In this study, we investigated the changes in frequency of occurrence and antimicrobial susceptibility pattern of blood isolates from 2005 to 2014. Methods: Data of blood isolates from Kosin Gospel Hospital during 2005 to 2014 were analyzed retrospectively. Blood isolates were cultured for 5 days using BACTEC Plus Aerobic/F and BACTEC lytic/10 Anaerobic/F. Identification and antimicrobial susceptibility test was performed using VITEK 1 system, VITEK 2 XL, PHOENIX 100 and conventional method. Results: 9,847 isolates were identified during 10 years. Among the isolates aerobic or falcutative anaerobic bacteria were isolated in 99.5% specimens, anaerobic were 0.1%, and fugi were 0.4%. Most commonly isolated bacteria were coagulase-negative Staphylococcus (CoNS) followed by Escherichia coli, Staphylococcus aureu s and Klebsiella pneumoniae. Candida parapsilosis were most frequently isolated among fungi. The proportion of S. aureus, A. baumannii and E. faecium were increased, while Pseud omonas aeruginosa and Streptococcu s p n e u m o n i a e d e c r e a s e d over decennium. Imipenem resistant K . p n e u m o n i a e were identified. Vancomycin resistant E. faecium and imipenem resistant A. baumannii were increased (7.1% in 2005 to 12.3% in 2014, 0% in 2005 to 55.6% in 2014, respectively). Conclusions: Over the last 10 year, CoNS were the most frequently isolated pathogen. Imipenem resistant K. p neumoniae was emerged. Vancomycin resistant E. faecium and imipenem resistant A. baumannii increased during this period.

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