지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 651 - 657 (7page)
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초록· 키워드
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Association between postoperative nausea and vomiting (PONV) and μ-opioid receptor A118G single nucleotide polymorphism (SNP) is undefined and might underlie inconsistent results of studies on PONV occurrence in patients undergoing general anesthesia with the opioid, remifentanil. Four hundred and sixteen Korean women undergoing breast surgery with general anesthesia were randomized to receive remifentanil 10 ng/mL (plasma-site, Minto model) using a target-controlled infusion device and either propofol for total intravenous anesthesia (T group) or sevoflurane for inhalation anesthesia (I group) with bispectral index values maintained between 40 and 60. Blood specimens were collected after anesthesia induction for A118G SNP analysis. PONV and postoperative pain were evaluated. A118G SNP type distribution among Korean female adults studied was AG (n = 195) > AA (n = 158) > GG (n = 63). Regardless of anesthetic technique, patients with GG types had lower PONV scale on arrival at postoperative care unit (PACU) (P = 0.002), while T group showed lower PONV scale than I group up to 6 hr after PACU discharge in AA and AG types. No differences were apparent for postoperative pain among opioid receptor polymorphism. PONV occurrence differs according to opioid receptor polymorphism and anesthetic technique in patients undergoing general anesthesia with remifentanil.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Stadler M / 2003 / Difference in risk factors for postoperative nausea and vomiting / Anesthesiology 98:46~52
Eikaas H / 2009 / Total intravenous anaesthesia techniques for ambulatory surgery / Curr Opin Anaesthesiol 22:725~729
Ahn HJ / 2008 / Comparison of surgical conditions during propofol or sevoflurane anaesthesia for endoscopic sinus surgery / Br J Anaesth 100:50~54
Coskun D / 2010 / Remifentanil versus fentanyl compared in a target-controlled infusion of propofol anesthesia : quality of anesthesia and recovery profile / J Anesth 24:373~379
Juckenhöfel S / 1999 / TIVA with propofol-remifentanil or balanced anesthesia with sevoflurane-fentanyl in laparoscopic operations. Hemodynamics, awakening and adverse effects / Anaesthesist 48:807~812
Eikaas H / 2009 / Total intravenous anaesthesia techniques for ambulatory surgery / Curr Opin Anaesthesiol 22:725~729
Ahn HJ / 2008 / Comparison of surgical conditions during propofol or sevoflurane anaesthesia for endoscopic sinus surgery / Br J Anaesth 100:50~54
Coskun D / 2010 / Remifentanil versus fentanyl compared in a target-controlled infusion of propofol anesthesia : quality of anesthesia and recovery profile / J Anesth 24:373~379
Juckenhöfel S / 1999 / TIVA with propofol-remifentanil or balanced anesthesia with sevoflurane-fentanyl in laparoscopic operations. Hemodynamics, awakening and adverse effects / Anaesthesist 48:807~812
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