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Background: This study was designed to determine the optimal anesthetic depth for the maintenance and recovery ininterventional neuroradiology. Methods: Eighty-eight patients undergoing interventional neuroradiology were randomly allocated to light anesthesia(n = 44) or deep anesthesia (n = 44) groups based on the value of the bispectral index (BIS). Anesthesia was inducedwith propofol, alfentanil, and rocuronium and maintained with 1−3% sevoflurane. The concentration of sevoflurane wastitrated to maintain BIS at 40−49 (deep anesthesia group) or 50−59 (light anesthesia group). Phenylephrine was used tomaintain the mean arterial pressure within 20% of preinduction values. Recovery times were recorded. Results: The light anesthesia group had a more rapid recovery to spontaneous ventilation, eye opening, extubation, andorientation (4.1 ± 2.3 vs. 5.3 ± 1.8 min, 6.9 ± 3.2 min vs. 9.1 ± 3.2 min, 8.2 ± 3.1 min vs. 10.7 ± 3.3 min, 10.0 ± 3.9 min vs. 12.9 ± 5.5 min, all P < 0.01) compared to the deep anesthesia group. The use of phenylephrine was significantly increasedin the deep anesthesia group (768 ± 184 vs. 320 ± 82 μg, P < 0.01). More patients moved during the procedure in the lightanesthesia group (6/44 [14%] vs. 0/44 [0%], P = 0.026). Conclusions: BIS values between 50 and 59 for interventional neuroradiology were associated with a more rapid recoveryand favorable hemodynamic response, but also with more patient movement. We suggest that maintaining BIS valuesbetween 40 and 49 is preferable for the prevention of patient movement during anesthesia for interventional neuroradiology.

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