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논문 기본 정보

자료유형
학술저널
저자정보
Yuan Yee Lee (Kyungpook National University) Yixian Quah (Korea Institute of Toxicology) Jung-Hae Shin (Kyungpook National University) Hyuk-Woo Kwon (Far East University) Dong-Ha Lee (Namseoul University) Jee Eun Han (Kyungpook National University) Jin-Kyu Park (Kyungpook National University) Sung Dae Kim (Kyungpook National University) Dongmi Kwak (Kyungpook National University) Seung-Chun Park (Kyungpook National University) Man Hee Rhee (Kyungpook National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.46 No.2
발행연도
2022.3
수록면
175 - 182 (8page)

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초록· 키워드

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Coronavirus disease 2019 (COVID-19) not only targets the respiratory system but also triggers a cytokine storm and a series of complications, such as gastrointestinal problems, acute kidney injury, and myocardial ischemia. The use of natural products has been utilized to ease the symptoms of COVID-19, and in some cases, to strengthen the immune system against COVID-19. Natural products are readily available and have been regularly consumed for various health benefits. COVID-19 has been reported to be associated with the risk of thromboembolism and deep vein thrombosis. These thrombotic complications often affects mortality and morbidity. Panax ginseng, which has been widely consumed for its various health benefits has also been reported for its therapeutic effects against cardiovascular disease, thrombosis and platelet aggregation. In this review, we propose that P. ginseng can be consumed as a supplementation against the various associated complications of COVID-19, especially against thrombosis. We utilized the network pharmacology approach to validate the potential therapeutic properties of P. ginseng against COVID-19 mediated thrombosis, the coagulation pathway and platelet aggregation. Additionally, we aimed to investigate the roles of P. ginseng against COVID-19 with the involvement of platelet-leukocyte aggregates in relation to immunity-related responses in COVID-19.

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ABSTRACT
1. Introduction
2. Thrombosis in COVID-19
3. Herbal supplementations and their proposed role for the treatment of COVID-19
4. The potential therapeutic effects of P. ginseng via network pharmacology
5. Current pharmacological approaches
6. Future perspectives
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