메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Hong Ki Ho (Department of Laboratory Medicine Yonsei University College of Medicine Seoul Korea) In Ji Won (Department of Laboratory Medicine Seoul Medical Center Seoul Korea) Lee Jaehyeon (Department of Laboratory Medicine Jeonbuk National University Medical School and Hospital Jeonju Ko) Kim So Yeon (Department of Laboratory Medicine National Medical Center Seoul Korea) Lee Kyoung Ah (Department of Laboratory Medicine Seoul Medical Center Seoul Korea) Kim Seunghyun (Department of Laboratory Medicine Seoul Medical Center Seoul Korea) An Yeoungim (Department of Laboratory Medicine Seoul Medical Center Seoul Korea) Lee Donggeun (Department of Laboratory Medicine Seoul Medical Center Seoul Korea) Sung Heungsup (University of Ulsan College of Medicine and Asan Medical Center Seoul Korea) Kim Jae-Seok (Department of Laboratory Medicine Hallym University College of Medicine Chuncheon Korea) Lee Hyukmin (Department of Laboratory Medicine Yonsei University College of Medicine Seoul Korea)
저널정보
대한진단검사의학회 Annals of Laboratory Medicine Annals of Laboratory Medicine 제42권 제1호
발행연도
2022.1
수록면
96 - 99 (4page)
DOI
10.3343/alm.2022.42.1.96

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
The sensitivity of molecular diagnostics could be affected by nucleotide variants in pathogen genes, and the sites affected by such variants should be monitored. We report a single-nucleotide variant (SNV) in the nucleocapsid (N) gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), i.e., G29179T, which impairs the diagnostic sensitivity of the Xpert Xpress SARS-CoV-2 assay (Cepheid, Sunnyvale, CA, USA). We observed significant differences between the threshold cycle (Ct) values for envelope (E) and N genes and confirmed the SNV as the cause of the differences using Sanger sequencing. This SNV, G29179T, is the most prevalent in Korea and is associated with the B.1.497 virus lineage, which is dominant in Korea. Clinical laboratories should be aware of the various SNVs in the SARS-CoV-2 genome and consider their potential effects on the diagnosis of coronavirus disease 2019.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0