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자료유형
학술저널
저자정보
Hye Won Lee (Department of Internal Medicine Yonsei University College of Medicine) Hankil Lee (College of Pharmacy Ajou University) Beom Kyung Kim (Department of Internal Medicine Yonsei University College of Medicin) Young Chang (Department of Internal Medicine Soonchunhyang University College of Medicine) Jae Young Jang (Department of Internal Medicine Soonchunhyang University College of Medicine) Do Young Kim (Department of Internal Medicine Yonsei University College of Medicine)
저널정보
대한간학회 Clinical and Molecular Hepatology Clinical and Molecular Hepatology 제28권 제2호
발행연도
2022.4
수록면
164 - 173 (10page)
DOI
10.3350/cmh.2021.0193

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Hepatitis C virus (HCV) infection is the second most common cause of chronic liver disease in South Korea, with a prevalence ranging from 0.6% to 0.8%, and HCV infection incidence increases with age. The anti-HCV antibody test, which is cheaper than the HCV RNA assay, is widely used to screen for HCV infections; however, the underdiagnosis of HCV is a major barrier to the elimination of HCV infections. Although several risk factors have been associated with HCV infections, including intravenous drug use, blood transfusions, and hemodialysis, most patients with HCV infections present with no identifiable risk factors. Universal screening for HCV in adults has been suggested to improve the detection of HCV infections. We reviewed the cost-effectiveness of HCV screening and the methodologies used to perform screening. Recent studies have suggested that universal HCV screening and treatment using direct-acting antivirals represent cost-effective approaches to the prevention and treatment of HCV infection. However, the optimal timing and frequency of HCV screening remain unclear, and further studies are necessary to determine the best approaches for the elimination of HCV infections.

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