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논문 기본 정보

자료유형
학술저널
저자정보
박지윤 (성균관대학교) Nammi Park (EOFLOW Co. Ltd.) Sangjin Han (EOFLOW Co. Ltd.) Lee You-Bin (Division of Endocrinology and Metabolism Department of Medicine Samsung Medical Center Sungkyunkwan) 김규리 (성균관대학교) Jin Sang-Man (Division of Endocrinology and Metabolism Department of Internal Medicine Samsung Medical Center Sun) 이우제 (울산대학교) 김재현 (삼성서울병원)
저널정보
대한당뇨병학회 Diabetes and Metabolism Journal Diabetes and Metabolism Journal Vol.46 No.6
발행연도
2022.11
수록면
941 - 947 (7page)
DOI
10.4093/dmj.2021.0299

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This study evaluated the safety and efficacy of tubeless patch pump called EOPatch in patients with well-controlled type 1 diabetes mellitus (T1DM). This 4-week, two-center, open-label, single-arm study enrolled 10 adult patients diagnosed with T1DM with glycosylated hemoglobin less than 7.5%. The co-primary end points were patch pump usage time for one attachment and number of serious adverse events related to the patch pump. The secondary end points were total amount of insulin injected per patch and changes in glycemic parameters including continuous glucose monitoring data compared to those at study entry. The median usage time per patch was 84.00 hours (interquartile range, 64.50 to 92.50). Serious adverse events did not occur during the trial. Four weeks later, time in range 70 to 180 mg/dL was significantly improved (70.71%±17.14 % vs. 82.96%±9.14%, <i>P</i>=0.01). The times spent below range (<54 mg/dL) and above range (>180 mg/dL) also improved (All <i>P</i><0.05). Four-week treatment with a tubeless patch pump was safe and led to clinical improvement in glycemic control.

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