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자료유형
학술저널
저자정보
Hoseok Jang (Department of Family Medicine Kyung Hee University Medical Center Seoul Korea) Sun Young Kim (Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Korea) Byung Sung Kim (Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Korea) Miji Kim (Department of Biomedical Science and Technology, College of Medicine/East-West Medical Research Institute, Kyung Hee University, Seoul, Korea) Jaehoon Jung (Department of Family Medicine Kyung Hee University Medical Center Seoul Korea) Chang Won Won (Department of Family Medicine College of Medicine Kyung Hee University Seoul Korea)
저널정보
대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.26 No.3
발행연도
2022.9
수록면
241 - 247 (7page)
DOI
10.4235/agmr.22.0092

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Background: Consumption and cognitive impairment are the most common health problems among older adults. This study aimed to determine the effects of functional constipation on cognitive decline in community-dwelling older adults. Methods: This was a 2-year longitudinal analysis of Korean Frailty and Aging Cohort Study data, including 851 community-dwelling residents who participated in both the baseline and follow-up surveys. A neuropsychological test, the Consortium to Establish a Registry for Alzheimer's Disease Assessment Battery (CERAD-K), and the Korean version of the Frontal Assessment Battery (FAB) were used to evaluate cognitive function. Functional constipation was defined according to the ROME IV criteria. An analysis of covariance was used to identify the association between functional constipation and cognitive decline. Results: Among the 851 participants, 8.9% had functional constipation. The patients in the constipation group were more likely to have low physical activity (15.8% vs. 8.8%), polypharmacy (61.8% vs. 45.5%), and depression (30.3% vs. 17.4%) than the non-constipation group. After adjusting for potential confounding factors, including age, sex, education years, low physical activity, polypharmacy, type 2 diabetes mellitus, depression, and baseline Cognitive Function Test score, the mean changes in Word Recognition test scores from 2018 to 2020 were -0.07 and -0.54 in the non-constipation and constipation groups, respectively (p=0.007). Other cognitive function tests (Mini-Mental State Examination, word list memory, word list recall, digit span, trail-making test, and FAB) did not show any difference in decline between the two groups (p>0.05). Conclusions: Functional constipation at baseline was associated with a decline in word recognition after 2 years.

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