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논문 기본 정보

자료유형
학술저널
저자정보
Yukako Nakagami (Department of Psychiatry Kyoto University Graduate School of Medicine) Kohei Hayakawa (Kyushu University) Toru Horinouchi (Department of Neuroscience Trafford Centre for Medical Research Brighton and Sussex Medical School) Victor Pereira-Sanchez (Department of Child and Adolescent Psychiatry NYU Grossman School of Medicine) Marcus P.J. Tan (Department of Child and Adolescent Psychiatry Institute of Psychiatry Psychology and Neuroscience K) Park Seon-Cheol (Department of Psychiatry Hanyang University Guri Hospital) Park Yong Chon (Department of Psychiatry Hanyang University Guri Hospital) Moon Seok Woo (Department of Psychiatry Konkuk University Chungju Hospital Institute of Medical Science) Choi Tae Young (Department of Psychiatry Catholic University of Daegu School of Medicine) Ajit Avasthi (Department of Psychiatry Post Graduate Institute of Medical Education and Research) Sandeep Grover (Department of Psychiatry Post Graduate Institute of Medical Education and Research) Roy Abraham Kallivayalil (Department of Psychiatry Pushpagiri Institute of Medical Sciences) Yugesh Rai (Essex Partnership University Trust) Mohammadreza Shalbafan (Mental Health Research Center Iran University of Medical Sciences) Pavita Chongsuksiri (Buddhachinaraj Hospital Phitsanulok) Pichet Udomratn (Department of Psychiatry Faculty of Medicine Prince of Songkla University) Samudra T. Kathriarachchi (Department of Psychiatry Faculty of Medical Sciences University of Sri Jayewardenepura) Yu-Tao Xiang (Unit of Psychiatry Department of Public Health and Medicinal Administration University of Macau) Kang Sim (Institute of Mental Health Buangkok Green Medical Park) Afzal Javed (Pakistan Psychiatric Research Centre Fountain House) Mian-Yoon Chong (Kaohsiung & Chang Gung University School of Medicine) Chay-Hoon Tan (Department of Pharmacology National University of Singapore) Shih-Ku Lin (Department of Psychiatry Linkou Chang Gung Memorial Hospital) Toshiya Inada (Department of Psychiatry Nagoya University Graduate School of Medicine) Toshiya Murai (Department of Psychiatry Kyoto University Graduate School of Medicine) Shigenobu Kanba (Kyushu University) Norman Sartorius (Association for the Improvement of Mental Health Programmes) Naotaka Shinfuku (Department of Social Welfare School of Human Sciences Seinan Gakuin University) Takahiro A. Kato (Department of Neuropsychiatry Graduate School of Medical Sciences Kyushu University)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제18권 제11호
발행연도
2021.11
수록면
1,058 - 1,067 (10page)
DOI
10.30773/pi.2021.0169

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Objective Recently, rational polypharmacy approaches have been proposed, regardless of the lower risk and cost of monotherapy. Considering monotherapy as first-line treatment and polypharmacy as rational treatment, a balanced attitude toward polypharmacy is recommended. However, the high prevalence of polypharmacy led the Japanese government to establish a polypharmacy reduction policy. Based on this, the association between the policy and psychiatrists’ attitude toward polypharmacy has been under debate.Methods We developed an original questionnaire about Psychiatrists’ attitudes toward polypharmacy (PAP). We compared the PAP scores with the treatment decision-making in clinical case vignettes. Multiple regression analyses were performed to quantify associations of explanatory variables including policy factors and PAP scores. The anonymous questionnaires were administered to psychiatrists worldwide.Results The study included 347 psychiatrists from 34 countries. Decision-making toward polypharmacy was associated with high PAP scores. Multiple regression analysis revealed that low PAP scores were associated with the policy factor (β=-0.20, p=0.004). The culture in Korea was associated with high PAP scores (β=0.34, p<0.001), whereas the culture in India and Nepal were associated with low scores (β=-0.15, p=0.01, and β=-0.17, p=0.006, respectively).Conclusion Policy on polypharmacy may influence psychiatrists’ decision-making. Thus, policies considering rational polypharmacy should be established.

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