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논문 기본 정보

자료유형
학술저널
저자정보
Yasemin Özkan (Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Adnan Menderes University) Mehmet Turgut (Department of Neurosurgery Faculty of Medicine Adnan Menderes University Aydin Turkey) Yasemin Turan (Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Adnan Menderes University) Mehmet Dinçer Bilgin (Department of Biophysics Faculty of Medicine Adnan Menderes University Aydin Turkey) Sinem Sari (Department of Anesthesia Faculty of Medicine Adnan Menderes University Aydin Turkey) Mustafa Yilmaz (Department of Biochemistry Adnan Menderes University School of Medicine) Yiğit Uyanikgil (Department of Histology-Embryology Ege University Izmir Turkey) Mahmut Alp Kiliç (Department of Biophysics Faculty of Medicine Adnan Menderes University Aydin Turkey) Derya Tanriöver (Department of Histology-Embryology Ege University Izmir Turkey) Zehra Seznur Kasar (Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Adnan Menderes University)
저널정보
대한약침학회 Journal of Acupuncture & Meridian Studies Journal of Acupuncture & Meridian Studies Vol.14 No.5
발행연도
2021.10
수록면
176 - 182 (7page)

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Background: Development of methods to accelerate nerve regeneration in peripheral nerve damage is important. Electroacupuncture is a new therapeutic method that combines traditional acupuncture with modern electrotherapy. Melatonin has been shown to reduce nerve damage. Objectives: In this study, we aimed to determine and compare the therapeutic effects of electroacupuncture and melatonin on rat sciatic nerve injury. Methods: A total of 56 adult male Wistar Albino rats were divided into four study groups with 14 animals in each group: intact control (group I), subcutaneous saline (group II), subcutaneous melatonin (group III), and electroacupuncture (group IV). Surgical procedure including unilateral (right) sciatic nerve injury was applied to groups II, III, and IV. Saline and melatonin started immediately after surgery for six weeks, while electroacupuncture was given two weeks after surgery for 3 weeks. Functional and histological assessments were used as outcome measurements. Results: Sciatic nerve damage caused a significant decrease in nerve conduction velocity. Both electroacupuncture treatment and melatonin treatment significantly increased the nerve conduction velocity. Both sciatic functional recovery and histological regeneration were faster in these treatment groups compared to the saline. However, no significant difference was observed between the two treatment groups. Conclusion: Electroacupuncture and melatonin are promising alternative treatment strategies for peripheral nerve damage and can be examined in detail in future studies.

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