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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
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- 대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제38권 제8호
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- 2016.8
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- 1 - 6 (6page)
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초록· 키워드
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Background: The purpose of this study was to compare the expression levels of p65 and S100 in the rat masseter muscle after the injection of different concentrations of botulinum toxin-A (BTX-A).
Methods: We injected either 5 or 10 U of BTX-A into both masseter muscle of rats. As a control group, the same volume of saline was injected. After 14 days, the animals were sacrificed. Subsequently, a biopsy and immunohistochemical staining of the samples were performed using a p65 or S100 antibody.
Results: The cross-sectional area of each myofibril was significantly reduced by BTX-A injection (P < 0.001). The expression of p65 and S100 increased significantly with increasing concentrations of BTX-A (P < 0.001).
Conclusions: The injection of BTX-A into the masseter muscle induced muscle atrophy. Subsequently, p65 and S100 expression in myoblasts were increased for the protection of muscle cells.
목차
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참고문헌 (32)
참고문헌 신청
Burgen A / 1949 / The action of botulinum toxin on the neuro-muscular junction / J Physiol 109:10~23
Schiavo G / 1992 / Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin / Nature 359:832~835
Jia-Zeng Su / 2015 / Microvascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca / Maxillofacial Plastic Reconstructive Surgery 37(1):1~4
Navarrete AL / 2013 / Botulinum neurotoxin type A in the masseter muscle: effects on incisor eruption in rabbits / Am J Orthod Dentofacial Orthop 143:499~506
Si-Yeok Park1, / 2015 / Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study / Maxillofacial Plastic Reconstructive Surgery 37(3):1~5
Schiavo G / 1992 / Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin / Nature 359:832~835
Jia-Zeng Su / 2015 / Microvascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca / Maxillofacial Plastic Reconstructive Surgery 37(1):1~4
Navarrete AL / 2013 / Botulinum neurotoxin type A in the masseter muscle: effects on incisor eruption in rabbits / Am J Orthod Dentofacial Orthop 143:499~506
Si-Yeok Park1, / 2015 / Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study / Maxillofacial Plastic Reconstructive Surgery 37(3):1~5
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