지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 349 - 355 (7page)
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초록· 키워드
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Purpose: We investigated improvements in overactive bladder symptoms and depressive symptoms after solifenacin treatment in overactive bladder patients with or without depressive symptoms.
Methods: We performed a prospective study of patients who had been diagnosed with overactive bladder from July 2013 to June 2014. Based on the Beck Depression Inventory questionnaire, the test subjects were divided into group 1, without depressive symptoms (0?9 points), and group 2, with depressive symptoms (10 or more points). The patients were administered 5 mg of solifenacin for 3 months. The following outcomes were analyzed at the first visit, 4 weeks, and 12 weeks: the overactive bladder symptom score (OABSS), International Prostate Symptom Score (IPSS), patients’ perceptions of their bladder condition, and the Beck Depression Inventory.
Results: A total of 72 patients participated, and 52 patients completed the study. Most outcome measures showed improvements in both groups at weeks 4 and 12. Especially in group 2, the questionnaires showed significant improvements from baseline to week 12, indicating that solifenacin was effective at treating overactive bladder symptoms (group 1 vs. group 2: OABSS, ?2.67±0.80 vs. ?3.00±0.77; P<0.01; IPSS-total, ?2.14±2.15 vs. ?4.94±1.70; P<0.01). Statistically significant decreases in the Beck Depression Inventory score from baseline to weeks 4 and 12 were observed in group 2 (group 1 vs. group 2: 1.43±0.74 vs. ?2.68±4.05 at week 4, P<0.001; 0.10±3.37 vs. ?5.52±5.82 at week 12, P<0.001).
Conclusions: In overactive bladder patients with depressive symptoms, solifenacin can help improve quality of life and depressive symptoms at the same time.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Wein AJ / 2003 / Diagnosis and treatment of the overactive bladder / Urology 62(5 Suppl 2):20~27
Coyne KS / 2011 / National community prevalence of overactive bladder in the United States stratified by sex and age / Urology 77:1081~1087
Ganz ML / 2010 / Economic costs of overactive bladder in the United States / Urology 75:526~532
Liberman JN / 2001 / Health-related quality of life among adults with symptoms of overactive bladder: results from a U.S. community-based survey / Urology 57:1044~1050
Coyne KS / 2008 / The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well-being in men and women: results from the EPIC study / BJU Int 101:1388~1395
Coyne KS / 2011 / National community prevalence of overactive bladder in the United States stratified by sex and age / Urology 77:1081~1087
Ganz ML / 2010 / Economic costs of overactive bladder in the United States / Urology 75:526~532
Liberman JN / 2001 / Health-related quality of life among adults with symptoms of overactive bladder: results from a U.S. community-based survey / Urology 57:1044~1050
Coyne KS / 2008 / The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well-being in men and women: results from the EPIC study / BJU Int 101:1388~1395
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