지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.12
- 수록면
- 132 - 137 (6page)
- DOI
- https://doi.org/10.12701/yujm.2015.32.2.132
이용수
초록· 키워드
오류제보하기
Adrenocorticotropic hormone (ACTH)-producing pheochromocytoma has been rarely reported, whereas only a few cases of Cushing syndrome accompanied by opportunistic infections have been reported. We experienced a patient with pheochromocytoma with ectopic Cushing syndrome complicated by invasive aspergillosis. A 35-year-old woman presented with typical Cushingoid features. Her basal plasma cortisol, ACTH, and 24-hour urine free cortisol levels were significantly high, and 24-hour urine metanephrine and catecholamine levels were slightly elevated. The endogeneous cortisol secretion was not suppressed by either low- or high-dose dexamethasone. Abdominal computed tomography (CT) revealed a heterogeneous enhancing mass measuring approximately 2.5 cm in size in the left adrenal gland. No definitive mass lesion was observed on sellar magnetic resonance imaging. On fluorine-18 fluorodeoxyglucose positron emission tomography/CT, a hypermetabolic nodule was observed in the left upper lung. Thus, we performed a percutaneous needle biopsy, which revealed inflammation, not malignancy. Thereafter, we performed a laparoscopic left adrenalectomy, and its pathologic finding was a pheochromocytoma with positive immunohistostaining for ACTH. After surgery, the biochemistry was normalized, but the clinical course was fatal despite intensive care because of the invasive aspergillosis that included the lungs, retina, and central nervous system.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Newell-Price J / 2006 / Cushing’s syndrome / Lancet 367(9522):1605~1617
Isidori AM / 2006 / The ectopic adrenocorticotropin syndrome:clinical features, diagnosis, management, and long-term follow-up / J Clin Endocrinol Metab 91:371~377
Ilias I / 2005 / Cushing’s syndrome due to ectopic corticotropin secretion:twenty years’ experience at the National Institutes of Health / J Clin Endocrinol Metab 90:4955~4962
Salgado LR / 2006 / Ectopic ACTH syndrome:our experience with 25 cases / Eur J Endocrinol 155:725~733
Bhansali A / 2009 / Ectopic Cushing’s syndrome: experience from a tertiary care centre / Indian J Med Res 129:33~41
Isidori AM / 2006 / The ectopic adrenocorticotropin syndrome:clinical features, diagnosis, management, and long-term follow-up / J Clin Endocrinol Metab 91:371~377
Ilias I / 2005 / Cushing’s syndrome due to ectopic corticotropin secretion:twenty years’ experience at the National Institutes of Health / J Clin Endocrinol Metab 90:4955~4962
Salgado LR / 2006 / Ectopic ACTH syndrome:our experience with 25 cases / Eur J Endocrinol 155:725~733
Bhansali A / 2009 / Ectopic Cushing’s syndrome: experience from a tertiary care centre / Indian J Med Res 129:33~41
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