Predictors for the Transition from Ductal Carcinoma In Situ to Invasive Breast Cancer in Korean Patients

Eun Young Kim; Kee Hoon Hyun; Yong Lai Park; Chan Heun Park; Sung-Im Do

doi:http://dx.doi.org/10.14449/jbd.2016.4.1.16

추천

검색

자료유형: 학술저널

저자정보: Eun Young Kim (Departments of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Kee Hoon Hyun (Departments of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Yong Lai Park (Departments of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Chan Heun Park (Department of Surgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul) Sung-Im Do (Departments of Pathology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine)

저널정보: 한국유방암학회 Journal of Breast Disease Journal of Breast Disease 제4권 제1호

발행연도: 2016.6

수록면: 16 - 23 (8page)

DOI: http://dx.doi.org/10.14449/jbd.2016.4.1.16

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Purpose: To identify predictive factors of upstaging from diagnosed ductal carcinoma in situ (DCIS) to invasive cancer after surgical excision. Methods: One hundred seventy-four patients diagnosed with DCIS based on biopsies between January 2009 and December 2014 were evaluated. Patients’ clinicopathological variables were assessed to identify predictive factors of invasive carcinoma from final pathology. Results: One hundred seventy-four cases of DCIS were included. Of these, 42 were upstaged to invasive carcinoma on the final excision. Preoperative features such as age 40 years or younger at diagnosis, presence of a palpable mass, ultrasonography (USG)-guided core needle biopsy, tumor size ≥20 mm on USG, high grade DCIS, cribriform DCIS, comedo necrosis, presence of intraluminal calcification, estrogen receptor negativity, progesterone receptor negativity and triple-negative subtype were significantly associated with the risk of invasive carcinoma. Multivariate analysis showed that a tumor size ≥20 mm on USG and triple negative subtype were independently associated with upstaging. Conclusion: Tumor size ≥20 mm on USG and triple-negative subtype were independently associated with the upstaging of DCIS to invasive cancer.

#Breast neoplasms #Noninfiltrating intraductal carcinoma

참고문헌 (29)

참고문헌 신청

Darling ML / 2000 / Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision / AJR Am J Roentgenol 175:1341~1346

Wahedna Y / 2001 / Mammographic size of ductal carcinoma in situ does not predict the presence of an invasive focus / Eur J Cancer 37:459~462

Jackman RJ / 2001 / Stereotactic breast biopsy of nonpalpable lesions: determinants of ductal carcinoma in situ underestimation rates / Radiology 218:497~502

King TA / 2001 / A mass on breast imaging predicts coexisting invasive carcinoma in patients with a core biopsy diagnosis of ductal carcinoma in situ / Am Surg 67:907~912

Cox D / 2006 / The significance of mammotome core biopsy specimens without radiographically identifiable microcalcification and their influence on surgical management: a retrospective review with histological correlation / Breast 15:210~218

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!