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논문 기본 정보

자료유형
학술저널
저자정보
Tian Zhong (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Qu Shifang (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Yana Chen (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Fang Jiaxin (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University,) Song Xingxu (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) He Kai (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Jiang Kexin (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Sun Xiaoyue (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Shi Jianyang (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Tao Yuchun (Department of Epidemiology and Biostatistics, School of Public Health, Jilin University) Jin Lina (Jilin University, China)
저널정보
한국역학회 Epidemiology and Health Epidemiology and Health Vol.46
발행연도
2024.1
수록면
1 - 9 (9page)
DOI
10.4178/epih.e2024020

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초록· 키워드

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OBJECTIVES: The magnesium depletion score (MDS) is considered more reliable than traditional approaches for predicting magnesium deficiency in humans. We explored the associations of MDS and dietary magnesium intake with diabetes. METHODS: We obtained data from 18,853 participants in the National Health and Nutrition Examination Survey 2011-2018. Using multivariate regression and stratified analysis, we investigated the relationships of both MDS and magnesium intake with diabetes. To compute prevalence ratios (PRs), we employed modified Poisson or log-binomial regression. We characterized the non-linear association between magnesium intake and diabetes using restricted cubic spline analysis. RESULTS: Participants with MDS ≥ 2 exhibited a PR of 1.26 (95% confidence interval [CI], 1.19 to 1.34) for diabetes. Per-standard deviation (SD) increase in dietary magnesium intake was associated with a lower prevalence of diabetes (PR, 0.91; 95% CI, 0.87 to 0.96). Subgroup analyses revealed a positive association between MDS ≥ 2 and diabetes across all levels of dietary magnesium intake, including the lowest (PR, 1.35; 95% CI, 1.18 to 1.55), middle (PR, 1.23; 95% CI, 1.12 to 1.35), and highest tertiles (PR, 1.25; 95% CI, 1.13 to 1.37; pinteraction< 0.001). Per-SD increase in magnesium intake was associated with lower diabetes prevalence in participants with MDS < 2 (PR, 0.92; 95% CI, 0.87 to 0.98) and those with MDS ≥ 2 (PR, 0.91; 95% CI, 0.84 to 0.98; pinteraction= 0.030). CONCLUSIONS: MDS is associated with diabetes, particularly among individuals with low magnesium intake. Adequate dietary magnesium intake may reduce diabetes risk, especially in those with high MDS.

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