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논문 기본 정보

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학술저널
저자정보
Marius Otto (Department of Pediatric Surgery, Pediatric Urology and Pediatric Orthopedics, DRK Children’s Hospital Siegen) Andreas Nef (Department of Oral and Maxillofacial Surgery, University Hospital Marburg) Thomas Ziebart (Department of Oral and Maxillofacial Surgery, University Hospital Marburg) Frank Halling (Department of Oral and Maxillofacial Surgery, University Hospital Marburg)
저널정보
대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science Vol.54 No.3
발행연도
2024.6
수록면
139 - 148 (10page)
DOI
10.5051/jpis.2204860243

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Purpose: The objective of this study was to demonstrate the suitability of cone-beam computed tomography (CBCT) for in vivo research in periodontology, with implications for oral implantology, facial traumatology, and all disciplines involved in treating patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ). Methods: Halves of the jaws of 9 Swiss mountain sheep, assigned to a control group (n=3), an osteoporosis group (n=3) and a zoledronate-exposed group (n=3), were examined. Clinical and radiological evaluations were conducted using CBCT imaging to assess whether periodontitis and bone defects were observed to a significant extent after surgical tooth extraction. Results: In contrast to the control and osteoporosis groups, the zoledronate group exhibited significant residual bone defects following tooth extraction (P<0.05). CBCT more objectively revealed these effects and enabled a numerical evaluation (in mm3 ). Conclusions: Evaluating residual defects in bone blocks from sheep using CBCT analysis was found to be as effective as a clinical examination conducted by specialists in oral and maxillofacial surgery. The strong correlation between radiological findings and clinical conditions suggests that CBCT may become increasingly important in the future, particularly in periodontological research related to BRONJ.

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