지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 105 - 112 (8page)
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초록· 키워드
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Objectives：The aim of this study was to investigate the relationship between blood pressure(BP) and cognitive function in the elderly with diabetes mellitus(DM).
Methods：A total of 68 patients with DM aged 65≥ years were included in this cross-sectional study. Relationships between BP and cognitive function tests were determined using Spearman’s rank correlations and multiple regression models.
Results：Higher diastolic BP(DBP) was associated with lower score on Mini-Mental State Examination(MMSE)(p=0.009), less verbal fluency test(p=0.007) and poorer digit span test(DST)(p=0.014). The relationship of verbal fluency test(VFT) and DBP was not attenuated after adjusting for covariates: age, gender, body mass index, depressive symptoms, education, duration of DM and quality of sleep in multivariable model. However, DBP could be predictor of MMSE and DST only after controlling for body mass index.
Conclusion：The result of this study indicates that elevated DBP in elderly with DM were associated with poorer cognitive performance, particularly semantic memory. Also this study demonstrated that verbal fluency was related to DBP after multivariate adjustment. This study underlines the importance of cognitive evaluation in elderly DM patients, and suggests that a high DBP may have deleterious effects on cognitive functions.
Methods：A total of 68 patients with DM aged 65≥ years were included in this cross-sectional study. Relationships between BP and cognitive function tests were determined using Spearman’s rank correlations and multiple regression models.
Results：Higher diastolic BP(DBP) was associated with lower score on Mini-Mental State Examination(MMSE)(p=0.009), less verbal fluency test(p=0.007) and poorer digit span test(DST)(p=0.014). The relationship of verbal fluency test(VFT) and DBP was not attenuated after adjusting for covariates: age, gender, body mass index, depressive symptoms, education, duration of DM and quality of sleep in multivariable model. However, DBP could be predictor of MMSE and DST only after controlling for body mass index.
Conclusion：The result of this study indicates that elevated DBP in elderly with DM were associated with poorer cognitive performance, particularly semantic memory. Also this study demonstrated that verbal fluency was related to DBP after multivariate adjustment. This study underlines the importance of cognitive evaluation in elderly DM patients, and suggests that a high DBP may have deleterious effects on cognitive functions.
목차
서론
대상 및 방법
결과
고찰
참고문헌
참고문헌 (35)
참고문헌 신청
[학술지(정기간행물)] - Kukull WA / 2002 / Dementia and Alzheimer disease incidence: a prospective cohort study / Arch Neurol 59 : 1737 ~ 1746
[학술지(정기간행물)] - Black BS / 2012 / Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures / Qual Life Res 21 : 1379 ~ 1389
[학술지(정기간행물)] - Reese JP / 2011 / Cost and care of patients with Alzheimer’s disease: clinical predictors in German health care settings / J Alzheimers Dis 27 : 723 ~ 736
[학술지(정기간행물)] - Halling A / 2006 / Association of diagnosis of ischemic heart disease, diabetes mellitus and heart failure with cognitive function in the elderly population / Eur J Gen Pract 12 : 114 ~ 119
[학술지(정기간행물)] - Alvarenga PP / 2010 / Functional mobility and executive function in elderly diabetics and non-diabetics / Rev Bras Fisioter 14 : 491 ~ 496
[학술지(정기간행물)] - Black BS / 2012 / Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures / Qual Life Res 21 : 1379 ~ 1389
[학술지(정기간행물)] - Reese JP / 2011 / Cost and care of patients with Alzheimer’s disease: clinical predictors in German health care settings / J Alzheimers Dis 27 : 723 ~ 736
[학술지(정기간행물)] - Halling A / 2006 / Association of diagnosis of ischemic heart disease, diabetes mellitus and heart failure with cognitive function in the elderly population / Eur J Gen Pract 12 : 114 ~ 119
[학술지(정기간행물)] - Alvarenga PP / 2010 / Functional mobility and executive function in elderly diabetics and non-diabetics / Rev Bras Fisioter 14 : 491 ~ 496
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UCI(KEPA) : I410-ECN-0101-2016-513-001657504