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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.9
- 수록면
- 39 - 46 (8page)
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초록· 키워드
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Objectives: The present study aimed at investigating the effects of Schisandrae Fructus (SF) on menopause symptoms in ovariectomized mice.
Methods: 6 weeks old female mice were ovariectomized (OVX), and the OVX mice were fed with a three doses of SF (25, 100, and 400 mg/kg, respectively) or 17β-estradiol (E2, 0.5 mg/kg) 3 times a week for 6 weeks. Body weight was measured at every week and uterus weight was also measured at the end of experiment. Lipids and osteocalcin levels in serum were analyzed.
Results: The uterine weight was not changed in SF treated group, while E2 intake increased the reduced uterine weight by OVX. Although Body weight was increased since two weeks after ovariectomy compared with sham operated group, there was no change in SF or E2 treated group compared with OVX. But LDL was significantly reduced in SF (400 mg/kg) or E2 fed mice and SF or E2 treatment decreased enhanced osteocalcin level by OVX.
Conclusion: These results indicated that SF would be effective in the improvement of LDL level and osteoporosis on menopause.
Methods: 6 weeks old female mice were ovariectomized (OVX), and the OVX mice were fed with a three doses of SF (25, 100, and 400 mg/kg, respectively) or 17β-estradiol (E2, 0.5 mg/kg) 3 times a week for 6 weeks. Body weight was measured at every week and uterus weight was also measured at the end of experiment. Lipids and osteocalcin levels in serum were analyzed.
Results: The uterine weight was not changed in SF treated group, while E2 intake increased the reduced uterine weight by OVX. Although Body weight was increased since two weeks after ovariectomy compared with sham operated group, there was no change in SF or E2 treated group compared with OVX. But LDL was significantly reduced in SF (400 mg/kg) or E2 fed mice and SF or E2 treatment decreased enhanced osteocalcin level by OVX.
Conclusion: These results indicated that SF would be effective in the improvement of LDL level and osteoporosis on menopause.
목차
서론
재료 및 방법
결과
고찰
결론
참고문헌
참고문헌 (17)
참고문헌 신청
[학술지(정기간행물)] - Archer DF / 2011 / Menopausal hot flushes and night sweats: where are we now? / Climacteric 14 : 515 ~ 528
[학술지(정기간행물)] - Body JJ / 2002 / Calcitonin for the long-term prevention and treatment of postmenopausal osteoporosis / Bone 30 (5 Suppl) : 75 ~ 79
[학술지(정기간행물)] - Ross RK / 2000 / Effect of hormone replacement therapy on breast cancer risk : estrogen versus estrogen plus progestin / J Natl Cancer Inst 92 (4) : 328 ~ 332
[학술지(정기간행물)] - Ziel HK / 1982 / Estrogen's role in endometrial cancer / Obstet Gynecol 60 : 509 ~ 515
[학술지(정기간행물)] - Nelson HD / 2002 / Postmenopausal hormone replacement therapy : scientific review / JAMA 288 (7) : 872 ~ 881
[학술지(정기간행물)] - Body JJ / 2002 / Calcitonin for the long-term prevention and treatment of postmenopausal osteoporosis / Bone 30 (5 Suppl) : 75 ~ 79
[학술지(정기간행물)] - Ross RK / 2000 / Effect of hormone replacement therapy on breast cancer risk : estrogen versus estrogen plus progestin / J Natl Cancer Inst 92 (4) : 328 ~ 332
[학술지(정기간행물)] - Ziel HK / 1982 / Estrogen's role in endometrial cancer / Obstet Gynecol 60 : 509 ~ 515
[학술지(정기간행물)] - Nelson HD / 2002 / Postmenopausal hormone replacement therapy : scientific review / JAMA 288 (7) : 872 ~ 881
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UCI(KEPA) : I410-ECN-0101-2017-519-001862532