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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.24 No.1
- 발행연도
- 2019.3
- 수록면
- 84 - 94 (11page)
- DOI
- 10.3746/pnf.2019.24.1.84
이용수
초록· 키워드
오류제보하기
Methanol extracts from ultraviolet (UV) C-irradiated mulberry leaves (UVC-IML) exhibit stronger tyrosinase and α-glucosidase inhibitory activities than those from unirradiated mulberry leaves. Through a bioassay-guided fractionation and purification process, two oxyresveratrol derivatives, oxyresveratrol (ORT) and 4’-prenyloxyresveratrol (PORT), and six 2-arylbenzofuran derivatives [moracin B (MCB), moracin C (MCC), moracin M (MCM), moracin N (MCN), 6,5’- dimethoxymoracin M (DMMCM), and chalcomoracin (CMC)] were isolated from the methanol extract from UVC-IML. Their chemical structures were determined by UV, mass, and nuclear magnetic resonance spectrometry. ORT and PORT showed potent tyrosinase inhibitory activities with the half maximal inhibitory concentration (IC50) values of 0.57 and 0.90 μM, respectively, and CMC exhibited significant tyrosinase and α-glucosidase inhibitory activity with IC50 values of 5.61 and 6.00 μM, respectively. Levels of these eight compounds were increased significantly following irradiation compared with untreated mulberry leaves; ORTs increased approximately 4 fold and moracins increased 2∼16 fold. These data suggest that UVC-IML may represent a promising source of nutraceuticals and cosmeceuticals for prevention of diabetes and skin aging.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (35)
참고문헌 신청
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Lee WC / 2003 / The study on the functional materials and effects of mulberry leaf / Food Science and Industry 36(3):2~14
Food Safety Korea / Mulberry leaf as a functional source of nutraceuticals in Korea
이선호 / 2015 / 무산소 처리에 의한 감마아미노뷰티르산(γ-Aminobutyric Acid) 함량이 높은 뽕잎차의 제조 / 한국식품과학회지 47(5):652~657
Chan EWC / 2016 / Phytochemistry, pharmacology, and clinical trials of Morus alba / Chin J Nat Med 14:17~30
Lee WC / 2003 / The study on the functional materials and effects of mulberry leaf / Food Science and Industry 36(3):2~14
Food Safety Korea / Mulberry leaf as a functional source of nutraceuticals in Korea
이선호 / 2015 / 무산소 처리에 의한 감마아미노뷰티르산(γ-Aminobutyric Acid) 함량이 높은 뽕잎차의 제조 / 한국식품과학회지 47(5):652~657
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UCI(KEPA) : I410-ECN-0101-2019-594-000543226