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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.2
- 수록면
- 21 - 25 (5page)
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초록· 키워드
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Trichomoniasis is the most common curable sexually-transmitted infection. Most Trichomonas vaginalis-infected men are asymptomatic and can remain undiagnosed and untreated, and this has been thought to result in chronic persistent prostatic infection. Chronic inflammation is regarded as the major factor in the pathogenesis and progression of benign prostatic hyperplasia (BPH) and prostatic cancer (PCa). The aim of this study is to identify seropositivity to T. vaginalis in men with prostate tumors (BPH or PCa) visited to Hanyang University Hospital. A total of 183 men were enrolled between October 2013 and November 2014. They consisted of 139 with BPH (mean age: 64.0±0.07) and 44 with prostate cancer (mean age: 73.3±0.18). We carried out ELISA to identify the seropositivity to T. vaginalis. Mixed lysate antigen extracted from 8 strains of T. vaginalis was used in the ELISA. Also 58 male outpatients visited to Health Promotion Center in Hanyang University Hospital were evaluated for comparing group. As a results, seropositivity to T. vaginalis in patients with prostatic diseases was 19.7% (BPH: 18.7%, PCa: 22.7%) and it was significantly higher than the 1.7% of the comparing healthy group (P=0.001). Therefore, prostatic tumor showed higher seropositivity against T. vaginalis than normal men. As far as we know, this is the first report about seroprevalence in prostatic tumor in Korea.
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참고문헌 (23)
참고문헌 신청
Gardner WA Jr / 1986 / Trichomonas vaginalis in the prostate gland / Arch Pathol Lab Med 110:430~432
Gardner WA Jr / 1987 / Subepithelial organisms in trichomonal cervicitis / Diagn Cytopathol 3:227~229
Grivennikov SI / 2010 / Immunity, inflammation, and cancer / Cell 140:883~899
Gurel B / 2014 / Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial / Cancer Epidemiol Biomarkers Prev 23:847~856
World Health Organization / 2012 / Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections-2008 :1~20
Gardner WA Jr / 1987 / Subepithelial organisms in trichomonal cervicitis / Diagn Cytopathol 3:227~229
Grivennikov SI / 2010 / Immunity, inflammation, and cancer / Cell 140:883~899
Gurel B / 2014 / Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial / Cancer Epidemiol Biomarkers Prev 23:847~856
World Health Organization / 2012 / Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections-2008 :1~20
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UCI(KEPA) : I410-ECN-0101-2019-513-000567809