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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제22권 제3호
- 발행연도
- 2017.1
- 수록면
- 145 - 152 (8page)
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초록· 키워드
오류제보하기
Growth hormone (GH) is important for promotion of somatic growth and the regulation of substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver, muscle, fat and pancreas either directly or indirectly through insulin-like growth factor 1. The diabetogenic action of GH has been well-described in previous in vivo studies. In this paper, we review the metabolic effects of GH on peripheral tissues focusing on glucose metabolism and insulin resistance, and discuss results from human studies on the long-term effects of GH administration on insulin resistance and hyperglycemia.
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등록된 정보가 없습니다.
참고문헌 (54)
참고문헌 신청
Woodmansee WW / 2010 / Occurrence of impaired fasting glucose in GH-deficient adults receiving GH replacement compared with untreated subjects / Clin Endocrinol (Oxf) 72:59~69
Elbornsson M / 2013 / Fifteen years of GH replacement improves body composition and cardiovascular risk factors / Eur J Endocrinol 168:745~753
Yuen KC / 2006 / Persisting effects on fasting glucose levels and insulin sensitivity after 6 months of discontinuation of a very low-dose GH therapy in adults with severe GH deficiency / Clin Endocrinol (Oxf) 64:549~555
Yuen KC / 2014 / Short-term, low-dose GH therapy improves insulin sensitivity without modifying cortisol metabolism and ectopic fat accumulation in adults with GH deficiency / J Clin Endocrinol Metab 99:E1862~E1869
Hartman ML / 2013 / Prospective safety surveillance of GHdeficient adults: comparison of GH-treated vs untreated patients / J Clin Endocrinol Metab 98:980~988
Elbornsson M / 2013 / Fifteen years of GH replacement improves body composition and cardiovascular risk factors / Eur J Endocrinol 168:745~753
Yuen KC / 2006 / Persisting effects on fasting glucose levels and insulin sensitivity after 6 months of discontinuation of a very low-dose GH therapy in adults with severe GH deficiency / Clin Endocrinol (Oxf) 64:549~555
Yuen KC / 2014 / Short-term, low-dose GH therapy improves insulin sensitivity without modifying cortisol metabolism and ectopic fat accumulation in adults with GH deficiency / J Clin Endocrinol Metab 99:E1862~E1869
Hartman ML / 2013 / Prospective safety surveillance of GHdeficient adults: comparison of GH-treated vs untreated patients / J Clin Endocrinol Metab 98:980~988
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