지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 843 - 851 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improvefunctional impairment are important. We assessed the effects of early exercise rehabilitation on functional outcomes in patientswith severe sepsis. Materials and Methods: A prospective, single-center, case-control study was conducted between January 2013 and May 2014 at a tertiary care center in Korea. Patients with severe sepsis and septic shock were enrolled and randomized to receive standard sepsistreatment or intervention. Intervention involved early targeted physical rehabilitation with sepsis treatment during hospitalization. Participants were assessed at enrollment, hospital discharge, and 6 months after enrollment. Functional recovery was measured using the Modified Barthel Index (MBI), Functional Independence Measure (FIM), and Instrumental Activities of Daily Living (IADL). Results: Forty participants (21 intervention patients) were included in an intention-to-treat analysis. There were no significant differences in baseline MBI, FIM, and IADL between groups. Intervention yielded greater improvement of MBI, FIM, and IADL in the intervention group at hospital discharge, but not significantly. Subgroup analysis of patients with APACHE II scores ≥10 showed significantly greater improvement of physical function at hospital discharge (MBI and FIM) in the intervention group, compared to the control group (55.13 vs. 31.75, p=0.048; 52.40 vs. 31.25, p=0.045). Intervention was significantly associated with improvement of MBI in multiple linear regression analysis (standardized coefficient 0.358, p=0.048). Conclusion: Early physical rehabilitation may improve functional recovery at hospital discharge, especially in patients with high initial severity scores.
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Heyland DK / 2000 / Longterm health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life / Crit Care Med 28:3599~3605
Hofhuis JG / 2008 / The impact of severe sepsis on health-related quality of life: a long-term follow-up study / Anesth Analg 107:1957~1964
Iwashyna TJ / 2010 / Long-term cognitive impairment and functional disability among survivors of severe sepsis / JAMA 304:1787~1794
Goodwin AJ / 2015 / Frequency, cost, and risk factors of readmissions among severe sepsis survivors / Crit Care Med 43:738~746
Prescott HC / 2014 / Increased 1-year healthcare use in survivors of severe sepsis / Am J Respir Crit Care Med 190:62~69
Hofhuis JG / 2008 / The impact of severe sepsis on health-related quality of life: a long-term follow-up study / Anesth Analg 107:1957~1964
Iwashyna TJ / 2010 / Long-term cognitive impairment and functional disability among survivors of severe sepsis / JAMA 304:1787~1794
Goodwin AJ / 2015 / Frequency, cost, and risk factors of readmissions among severe sepsis survivors / Crit Care Med 43:738~746
Prescott HC / 2014 / Increased 1-year healthcare use in survivors of severe sepsis / Am J Respir Crit Care Med 190:62~69
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