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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한응급의학회 Clinical and Experimental Emergency Medicine Clinical and Experimental Emergency Medicine Vol.7 No.3
- 발행연도
- 2020.1
- 수록면
- 150 - 160 (11page)
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초록· 키워드
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Objective The aim of the study was to compare the mortality rates of patients with early-identified (EI) sepsis and late-identified (LI) sepsis. Methods We performed a retrospective chart review of patients admitted to the emergency department and diagnosed with sepsis. EI sepsis was defined as patients with a Sequential Organ Failure Assessment (SOFA) score ≥2, based on 3 parameters of the SOFA score (Glasgow coma scale, mean arterial pressure, and partial pressure of oxygen/fraction of inspired oxygen ratio), measured within an hour of emergency department admission. The remaining patients were defined as LI sepsis. The primary outcome was in-hospital mortality. Results Of the total 204 patients with sepsis, 113 (55.4%) had EI sepsis. Overall mortality rate was 15.7%, and EI sepsis group had significantly higher mortality than LI sepsis (23.0% vs. 6.6%, P=0.003). The patients with EI sepsis, compared to those with LI sepsis, had higher SOFA score (median: 4 vs. 2, P<0.001); Acute Physiology and Chronic Health Evaluation (APACHE) II score (median: 14 vs. 10, P<0.001); were more likely to progress to septic shock within 6 hours after admission (17.7% vs. 1.1%, P<0.001); were more likely to be admitted to the intensive care unit (2.2% vs. 1.1%, P=0.001). Conclusion Mortality was significantly higher in the EI sepsis group than in the LI sepsis group.
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참고문헌 (25)
참고문헌 신청
Singer M / 2016 / The third international consensus definitions for sepsis and septic shock(Sepsis-3) / JAMA 315:801~810
Bossuyt PM / 2003 / Towards complete and accurate reporting of studies of diagnostic accuracy : the STARD initiative / BMJ 326:41~44
Simel DL / 2008 / The STARD statement for reporting diagnostic accuracy studies : application to the history and physical examination / J Gen Intern Med 23:768~774
Gilbert EH / 1996 / Chart reviews in emergency medicine research : Where are the methods / Ann Emerg Med 27:305~308
Vincent JL / 1996 / The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine / Intensive Care Med 22:707~710
Bossuyt PM / 2003 / Towards complete and accurate reporting of studies of diagnostic accuracy : the STARD initiative / BMJ 326:41~44
Simel DL / 2008 / The STARD statement for reporting diagnostic accuracy studies : application to the history and physical examination / J Gen Intern Med 23:768~774
Gilbert EH / 1996 / Chart reviews in emergency medicine research : Where are the methods / Ann Emerg Med 27:305~308
Vincent JL / 1996 / The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine / Intensive Care Med 22:707~710
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