지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 47 - 62 (16page)
이용수
초록· 키워드
오류제보하기
Glenditsia spina (GS) can resolve carbuncle, relive swelling, dispel wind and destroy parasites. For these reasons, GS has been widely used as dermatologic agent clinically. In this study, the specific pathways of
anti-proliferative effect of GS on human derived melanoma cells were identified. The molecular profile was measured using microarray technique to identify up- or down-regulated genes in SK-MEL-2 cell line.
Pathway analysis was done by listing percentage of pathway involvement, and the represented pathways were obtained from KEGG. The transcription factor binding sequences were obtained by Transfac database.
By the promoter analysis, up-regulated genes by GS were mainly associated with MAPK, Regulation of actin cytoskeleton, Wnt, Focal adhesion and Long term potentiation pathway. Down-regulated genes by GS were
mainly associated with MAPK and Antigen processing and presentation pathway. And some of the transcription factors like Sp1 and NF-Y in up-regulated genes and Oct-1 in down-regulated genes by GS also identified.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Blanchard AP / 1996 / High-density oligonucleotide arrays / Biosensors Bioelectron 11 : 687 ~ 690
Choi HJ / 2006 / Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases / Cancer Le
Florell SR / 2001 / Preservation of RNA for functional genomic studies: a multidisciplinary tumor bank protocol / Mod Pathol 14 (2) : 116 ~ 128
Galbraith DW / 2006 / The daunting process of MIAME / Nature 444 (7115) : 31 ~
Hong Y / 2007 / A susceptibility gene set for early onset colorectal cancer that integrates diverse signaling pathways: implication for tumorigenesis / Clin Cancer Res 13 (4)
Choi HJ / 2006 / Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases / Cancer Le
Florell SR / 2001 / Preservation of RNA for functional genomic studies: a multidisciplinary tumor bank protocol / Mod Pathol 14 (2) : 116 ~ 128
Galbraith DW / 2006 / The daunting process of MIAME / Nature 444 (7115) : 31 ~
Hong Y / 2007 / A susceptibility gene set for early onset colorectal cancer that integrates diverse signaling pathways: implication for tumorigenesis / Clin Cancer Res 13 (4)
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
DNA chip을 이용한 조각자 추출물의 인간유래 악성 종양에 미치는 영향
한방안이비인후피부과학회지
2008 .01
-
Gene Microarray Assessment of Multiple Genes and Signal Pathways Involved in Androgen-dependent Prostate Cancer Becoming Androgen Independent
Asian Pacific journal of cancer prevention : APJCP
2014 .01
-
Differentially Expressed Genes in Metastatic Advanced Egyptian Bladder Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Functional Gene Analysis to Identify Potential Markers Induced by Benzene in Two Different Cell Lines, HepG2 and HL-60
Molecular & cellular toxicology
2008 .01
-
Analysis of Key Genes and Pathways Associated with Colorectal Cancer with Microarray Technology
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
忍冬藤이 인간 유래 악성 흑색종 세포의 유전자 발현에 미치는 영향
한방안이비인후피부과학회지
2009 .01
-
반하가 천식이 유발된 생쥐 폐조직의 유전자 발현에 미치는 영향
한방안이비인후피부과학회지
2008 .01
-
Exploration of Molecular Mechanisms of Diffuse Large B-cell Lymphoma Development Using a Microarray
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
New Approaches to Functional Process Discovery in HPV 16-Associated Cervical Cancer Cells by Gene Ontology
Cancer Research and Treatment
2003 .01
-
Differential Gene Expression Profiling in Human Promyelocytic Leukemia Cells Treated with Benzene and Ethylbenzene
Molecular & cellular toxicology
2008 .01
-
최근 5년간의 국내.외 표준 진료 지침서(Critical Pathway) 연구논문분석 - 1995~1999년 -
한국의료질향상학회지
2000 .01
-
Critical Pathway의 임상 활용
한국의료질향상학회지
1999 .01
-
側柏葉이 인간 유래 악성 흑색종 세포의 유전자 발현에 미치는 영향
한방안이비인후피부과학회지
2010 .01
-
Critical Pathway의 이해
한국의료질향상학회지
1999 .01
-
Microarray Analysis of Gene Expression Alteration in Human Middle Ear Epithelial Cells Induced by Asian Sand Dust
Clinical and Experimental Otorhinolaryngology
2015 .01
-
Small Cell Melanoma
Annals of Dermatology
2014 .01
-
자궁적출술 환자를 위한 critical pathway 개발과 적용효과
Women's Health Nursing
2000 .01
-
Gene Expression Profile in Carpal Tunnel Syndrome Patients
Molecular & cellular toxicology
2006 .01
-
위절제술 환자의 표준진료지침 개발 및 적용 효과
한국의료질향상학회지
2003 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0