지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Background: In this study, we examined the influence of exercise loading characteristics on bone metabolic responses and bone morphology in the growth phase and adulthood.
Methods: Running exercise (RUN) and jumping exercise (JUM) were used for the exercise loading in 28-day-old male Wistar rats. Bone metabolism was measured by blood osteocalcin (OC) and tartrate-resistant acid phosphatase (TRACP) levels. For bone morphology, the maximum bone length, bone weight, and bone strength of the femur and tibia were measured. Results: A pre- and post-exercise loading comparison in the growth phase showed significantly increased OC levels in the RUN and JUM groups and significantly decreased TRACP levels in the JUM group. On the other hand, a pre- and post-exercise loading comparison in adulthood showed significantly decreased TRACP levels in the RUN and JUM groups. Femur lengths were significantly shorter in the RUN and JUM groups than in the control (CON) group, while bone weight was significantly greater in the JUM group than in the CON group. Conclusions: Exercise loading activates OC levels in the growth phase and suppresses TRACP levels in adulthood. On the other hand, these results suggest that excessive exercise loading may suppress bone length.
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참고문헌 (41)
참고문헌 신청
Martin T / 2009 / Molecular mechanisms in coupling of bone formation to resorption / Crit Rev Eukaryot Gene Expr 19:73~88
Lee S / 2012 / A change of osteocalcin(OC)and tartrate resistant acid phosphatase 5b(TRACP-5b)with the menstrual cycle / Horm Metab Res 44:699~703
Filaire E / 2012 / Reactive oxygen species and exercise on bone metabolism: friend or enemy? / Joint Bone Spine 79:341~346
Sindler AL / 2013 / Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles / J Appl Physiol 114:681~693
Ofek O / 2011 / CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts / J Bone Miner Res 26:308~316
Lee S / 2012 / A change of osteocalcin(OC)and tartrate resistant acid phosphatase 5b(TRACP-5b)with the menstrual cycle / Horm Metab Res 44:699~703
Filaire E / 2012 / Reactive oxygen species and exercise on bone metabolism: friend or enemy? / Joint Bone Spine 79:341~346
Sindler AL / 2013 / Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles / J Appl Physiol 114:681~693
Ofek O / 2011 / CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts / J Bone Miner Res 26:308~316
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