메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: Hypersensitivity to Rosaceae fruits, especially apple, is often associated with birch pollinosis. As the sensitization to pollens has increased, apple allergy is more prevalent. However, the immunologic mechanism has not yet been evaluated in Korean adult patients. Objective: This study was conducted to characterize the clinical features of apple allergy and to identify its IgE- binding components. Method: Ten patients having apple allergy were enrolled. Skin prick tests to common allergens and pollens were performed. Serum specific IgE to apple was measured by ELISA, and IgE-binding components of apple allergen were identified by IgE immunoblot analysis. Result: Most patients showed positive responses to alder/ birch pollens by skin prick tests and high serum levels of specific IgE to apple by ELISA. The IgE-binding component of apple allergen with a molecular weight of 17 kDa was identified by IgE immunoblot in most patients. There was no significant difference in the level of specific IgE to apple between the patient group having oral allergy syndrome and the other group with additional systemic symptoms. Conclusion: We confirmed that apple allergy can develop in pollen-sensitized patients because a 17-kDa allergen is assumed as Mal d 1 which shares a common allergenic determinant with Bet v 1 of birch pollen.

목차

등록된 정보가 없습니다.

참고문헌 (25)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0