지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
the genus Nocardia (N.), which are aerobic, filamentous, gram-positive bacilli. A definitive diagnosis depends on the isolation and identification of Nocardia species. But identification from clinical specimens may involve performing invasive techniques on the patient and lengthy process (take up to 1 or 3 weeks) owing to slow growth, and require a professional microbiologist. Currently the genus Nocardia is best identified using 16S rRNA and 18S rRNA gene sequence analysis. Recently matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has launched a new era in the routine microbiology laboratory. This method has proved its efficacy for the identification and diagnosis of microorganism. MALDI-TOF MS has potential for use as a rapid (within 1 hour) and dependable method for the identification of Nocardia species with reproducibility and cost effectiveness. We report a 76-year-old woman who suffered from ulcer with papules on her right wrist and forearm. A biopsy of the skin showed granulomatous inflammation with central suppuration. A bacterial isolate from the skin was identified to be N. brasiliensis on comparative 16S rRNA gene sequencing and MALDI-TOF MS.
To the best of our knowledge, this is the first case of nocardiosis in Korea caused by N. brasiliensis identified on MALDI-TOF MS.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Saubolle MA / 2003 / Nocardiosis : review of clinical and laboratory experience / J Clin Microbiol 41:4497~4501
신정우 / 2009 / 16S Ribosomal RNA로 진단한 Nocardia brasiliensis에 의한 파종성 피부 노카르디아증 1예 / 대한피부과학회지 47(9):1024~1028
강교신 / 2011 / Nocardia brasiliensis에 의한 일차성 피부 노카르디아증 / 대한피부과학회지 49(08):730~734
Verroken A / 2010 / Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of nocardia species / J Clin Microbiol 48:4015~4021
장우익 / 2007 / 폐암 환자에서 발생한 원발성 피부 Nocardia 감염증 1예 / 대한내과학회지 73(3):342~345
신정우 / 2009 / 16S Ribosomal RNA로 진단한 Nocardia brasiliensis에 의한 파종성 피부 노카르디아증 1예 / 대한피부과학회지 47(9):1024~1028
강교신 / 2011 / Nocardia brasiliensis에 의한 일차성 피부 노카르디아증 / 대한피부과학회지 49(08):730~734
Verroken A / 2010 / Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of nocardia species / J Clin Microbiol 48:4015~4021
장우익 / 2007 / 폐암 환자에서 발생한 원발성 피부 Nocardia 감염증 1예 / 대한내과학회지 73(3):342~345
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